NDN and U2AF1

Number of citations of the paper that reports this interaction (PubMedID 26871637)
108

Data Source:
BioGRID (two hybrid, two hybrid)

		NDN	U2AF1
Description		necdin, MAGE family member	U2 small nuclear RNA auxiliary factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Centrosome Cytosol Cell Projection Perikaryon	Nucleoplasm Spliceosomal Complex Cajal Body Nuclear Speck Catalytic Step 2 Spliceosome U2AF
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Gamma-tubulin Binding	RNA Binding Protein Binding Pre-mRNA 3'-splice Site Binding Metal Ion Binding
	Biological Process	Neuron Migration Respiratory System Process Nervous System Development Axonal Fasciculation Central Nervous System Development Negative Regulation Of Cell Proliferation Glial Cell Migration Post-embryonic Development Cytokine-mediated Signaling Pathway Sensory Perception Of Pain Regulation Of Growth Positive Regulation Of Transcription By RNA Polymerase II Neurotrophin TRK Receptor Signaling Pathway Axon Extension Multicellular Organismal Homeostasis Genetic Imprinting	MRNA Splicing, Via Spliceosome MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing
Pathways		Interleukin-4 and Interleukin-13 signaling	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases		Prader-Willi and Angelman syndromes, including: Angelman syndrome (AS); Prader-Willi syndrome (PWS)
GWAS		Depressive symptoms (SSRI exposure interaction) ( 25649181) Plasma anti-thyroid peroxidase levels ( 29678681) Serum metabolite concentrations in chronic kidney disease ( 29545352)	Blood and toenail selenium levels ( 25343990)
Interacting Genes		47 interacting genes: APBB1IP ARSL BLOC1S6 CALCOCO2 CCDC136 CDR2 DTNBP1 E2F1 E2F4 EEF1AKMT1 EGFR EID1 EPAS1 FAM131C FSD2 FXR2 GKAP1 GOLGA2 HIF1A HNRNPU IFFO1 IL1A IL32 IRS4 LAX1 LPXN MIER2 MKRN2 MPP6 MYG1 NEFL NGFR NUBP1 NUCB1 NUCB2 P4HA3 PJA1 PPARGC1A PPFIA1 SERTAD3 SIRT1 SSX2IP TFIP11 TP53 U2AF1 ZBTB1 ZBTB7B	38 interacting genes: AP2B1 CHERP CIR1 CLK2 DHX38 EPB41 FRA10AC1 HINFP HNRNPK HNRNPM IL7R JMJD6 MAP1B MFAP1 NDN NKAP NXF1 PABPC1 PRPF19 PRPF38A PRPF4 PRPF40A RBM10 RNPS1 RP9 SF3A3 SF3B2 SNRPD1 SRPK1 SRSF1 SRSF2 SUV39H1 TOE1 U2AF2 VEGFA ZCCHC10 ZRANB2 ZRSR2
Entrez ID		4692	7307
HPRD ID		03667	01871
Ensembl ID		ENSG00000182636	ENSG00000160201
Uniprot IDs		Q99608 X5D982	P0DN76 Q01081 Q7Z780
PDB IDs			1JMT
Enriched GO Terms of Interacting Partners?
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