NDN and ZBTB1

Number of citations of the paper that reports this interaction (PubMedID 26871637)
108

Data Source:
BioGRID (two hybrid, two hybrid)

		NDN	ZBTB1
Description		necdin, MAGE family member	zinc finger and BTB domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Centrosome Cytosol Cell Projection Perikaryon	Nucleus Nucleoplasm Nuclear Body Nuclear Membrane
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Gamma-tubulin Binding	DNA Binding Protein Binding Protein Homodimerization Activity Metal Ion Binding Protein Heterodimerization Activity K63-linked Polyubiquitin Modification-dependent Protein Binding
	Biological Process	Neuron Migration Respiratory System Process Nervous System Development Axonal Fasciculation Central Nervous System Development Negative Regulation Of Cell Proliferation Glial Cell Migration Post-embryonic Development Cytokine-mediated Signaling Pathway Sensory Perception Of Pain Regulation Of Growth Positive Regulation Of Transcription By RNA Polymerase II Neurotrophin TRK Receptor Signaling Pathway Axon Extension Multicellular Organismal Homeostasis Genetic Imprinting	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of T Cell Mediated Immunity DNA Repair Chromatin Remodeling Cellular Response To DNA Damage Stimulus Translesion Synthesis B Cell Differentiation Positive Regulation Of Natural Killer Cell Differentiation T Cell Differentiation In Thymus Cellular Response To UV MRNA Transcription By RNA Polymerase II Innate Immune Response Positive Regulation Of T Cell Differentiation Thymus Development Protein Homooligomerization Positive Regulation Of Pro-T Cell Differentiation
Pathways		Interleukin-4 and Interleukin-13 signaling
Drugs
Diseases		Prader-Willi and Angelman syndromes, including: Angelman syndrome (AS); Prader-Willi syndrome (PWS)
GWAS		Depressive symptoms (SSRI exposure interaction) ( 25649181) Plasma anti-thyroid peroxidase levels ( 29678681) Serum metabolite concentrations in chronic kidney disease ( 29545352)	Urinary albumin-to-creatinine ratio ( 31630189)
Interacting Genes		47 interacting genes: APBB1IP ARSL BLOC1S6 CALCOCO2 CCDC136 CDR2 DTNBP1 E2F1 E2F4 EEF1AKMT1 EGFR EID1 EPAS1 FAM131C FSD2 FXR2 GKAP1 GOLGA2 HIF1A HNRNPU IFFO1 IL1A IL32 IRS4 LAX1 LPXN MIER2 MKRN2 MPP6 MYG1 NEFL NGFR NUBP1 NUCB1 NUCB2 P4HA3 PJA1 PPARGC1A PPFIA1 SERTAD3 SIRT1 SSX2IP TFIP11 TP53 U2AF1 ZBTB1 ZBTB7B	17 interacting genes: AR EWSR1 FAM161A FANCG HEMGN LZTR1 MAML3 NDN PCNA PIM1 TRAF1 TRIM42 UBC UBE2I ZBTB25 ZNF417 ZNF572
Entrez ID		4692	22890
HPRD ID		03667	15688
Ensembl ID		ENSG00000182636	ENSG00000126804
Uniprot IDs		Q99608 X5D982	Q9Y2K1
PDB IDs
Enriched GO Terms of Interacting Partners?
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