IRS4 and MAGEL2

Number of citations of the paper that reports this interaction (PubMedID 28973533)
2

		IRS4	MAGEL2
Description		insulin receptor substrate 4	MAGE family member L2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane	Nucleus Endosome Early Endosome Cytosol Retromer Complex
	Molecular Function	SH3/SH2 Adaptor Activity Insulin Receptor Binding Protein Binding Phosphatidylinositol 3-kinase Binding	Ubiquitin-protein Transferase Activity Protein Binding
	Biological Process	Signal Transduction Insulin Receptor Signaling Pathway Positive Regulation Of Signal Transduction	Arp2/3 Complex-mediated Actin Nucleation Retrograde Transport, Endosome To Golgi Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Rhythmic Process Positive Regulation Of Actin Nucleation Protein K63-linked Ubiquitination
Pathways		IRS-related events triggered by IGF1R
Drugs
Diseases
GWAS			Menarche (age at onset) ( 25231870) Serum metabolite concentrations in chronic kidney disease ( 29545352)
Interacting Genes		21 interacting genes: CRK CRKL CSNK1G2 EGFR ERBB2 GRB2 IGF1R MAGEL2 MTNR1A MTNR1B NDN NISCH PIK3CA PIK3R1 PRKCZ PTPN11 PTPN6 RNF41 SOCS6 SOCS7 YWHAG	4 interacting genes: IRS4 PCGF6 RNF41 VPS52
Entrez ID		8471	54551
HPRD ID		04620	12008
Ensembl ID		ENSG00000133124	ENSG00000254585
Uniprot IDs		O14654	Q9UJ55
PDB IDs
Enriched GO Terms of Interacting Partners?
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