MAGEL2 and VPS52

Number of citations of the paper that reports this interaction (PubMedID 28973533)
2

Data Source:
BioGRID (two hybrid)

		MAGEL2	VPS52
Description		MAGE family member L2	VPS52 subunit of GARP complex
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Endosome Early Endosome Cytosol Retromer Complex	GARP Complex Golgi Apparatus Cytosol Endosome Membrane Membrane Trans-Golgi Network Membrane Perinuclear Region Of Cytoplasm Recycling Endosome EARP Complex
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding	Protein Binding Rab GTPase Binding Syntaxin Binding
	Biological Process	Arp2/3 Complex-mediated Actin Nucleation Retrograde Transport, Endosome To Golgi Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Rhythmic Process Positive Regulation Of Actin Nucleation Protein K63-linked Ubiquitination	Golgi To Vacuole Transport Lysosomal Transport Ectodermal Cell Differentiation Protein Transport Endocytic Recycling Retrograde Transport, Endosome To Golgi Embryonic Ectodermal Digestive Tract Development
Pathways			Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Menarche (age at onset) ( 25231870) Serum metabolite concentrations in chronic kidney disease ( 29545352)	Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971)
Interacting Genes		4 interacting genes: IRS4 PCGF6 RNF41 VPS52	50 interacting genes: AAMP ARNT2 ATP6V1D C1orf109 CACNA1A CCDC146 CCDC33 DDX6 EEF1AKNMT EPM2AIP1 FAM184A GFM2 GOLGA1 HAUS1 HEATR1 HGS KANK2 KIAA1217 KIF5B KLC3 LMO4 MAGEL2 MAPK3 MFAP1 MRPL11 NFKBIB NOP2 PIMREG PPP1R18 PRKAA1 PRKAA2 RAB4A RABEP2 SH2D4A STX11 TBC1D22B TCEANC TEAD4 THAP11 TPM3 TRAF6 TSSK3 TSTD2 TXLNA TXN2 USP2 VPS28 VPS53 WTAP ZMAT2
Entrez ID		54551	6293
HPRD ID		12008	09142
Ensembl ID		ENSG00000254585	ENSG00000223501
Uniprot IDs		Q9UJ55	A0A1U9X8S4 B3KMF7 B4DS44 Q4VXZ2 Q8N1B4
PDB IDs
Enriched GO Terms of Interacting Partners?
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