IRS4 and NISCH

Number of citations of the paper that reports this interaction (PubMedID 11912194)
11

Data Source:
HPRD (in vivo)

		IRS4	NISCH
Description		insulin receptor substrate 4	nischarin
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane	Cytoplasm Early Endosome Cytosol Plasma Membrane Membrane Recycling Endosome
	Molecular Function	SH3/SH2 Adaptor Activity Insulin Receptor Binding Protein Binding Phosphatidylinositol 3-kinase Binding	Integrin Binding Protein Binding Protein Kinase Binding Phosphatidylinositol Binding Identical Protein Binding
	Biological Process	Signal Transduction Insulin Receptor Signaling Pathway Positive Regulation Of Signal Transduction	Glucose Metabolic Process Apoptotic Process Regulation Of Blood Pressure Rac Protein Signal Transduction Actin Cytoskeleton Organization Negative Regulation Of Cell Migration Regulation Of Synaptic Transmission, GABAergic Norepinephrine Secretion
Pathways		IRS-related events triggered by IGF1R
Drugs			Tizanidine Agmatine Moxonidine
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972 31043756) General cognitive ability ( 29844566) Parkinson's disease ( 28892059) Schizophrenia ( 25056061 29483656 23974872) Waist-hip ratio ( 20935629)
Interacting Genes		21 interacting genes: CRK CRKL CSNK1G2 EGFR ERBB2 GRB2 IGF1R MAGEL2 MTNR1A MTNR1B NDN NISCH PIK3CA PIK3R1 PRKCZ PTPN11 PTPN6 RNF41 SOCS6 SOCS7 YWHAG	3 interacting genes: AR IRS4 ITGA5
Entrez ID		8471	11188
HPRD ID		04620	11391
Ensembl ID		ENSG00000133124	ENSG00000010322
Uniprot IDs		O14654	Q9Y2I1
PDB IDs			3P0C
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?