IRS4 and SOCS7

Number of citations of the paper that reports this interaction (PubMedID 12052866)
38

		IRS4	SOCS7
Description		insulin receptor substrate 4	suppressor of cytokine signaling 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane	Nucleus Cytosol Plasma Membrane Phosphatidylinositol 3-kinase Complex
	Molecular Function	SH3/SH2 Adaptor Activity Insulin Receptor Binding Protein Binding Phosphatidylinositol 3-kinase Binding	Protein Binding SH3 Domain Binding 1-phosphatidylinositol-3-kinase Regulator Activity
	Biological Process	Signal Transduction Insulin Receptor Signaling Pathway Positive Regulation Of Signal Transduction	Biological_process Negative Regulation Of Signal Transduction Protein Ubiquitination Intracellular Signal Transduction Regulation Of Growth Regulation Of Phosphatidylinositol 3-kinase Activity Phosphatidylinositol Phosphorylation
Pathways		IRS-related events triggered by IGF1R
Drugs
Diseases
GWAS			Ovarian cancer ( 23535730)
Interacting Genes		21 interacting genes: CRK CRKL CSNK1G2 EGFR ERBB2 GRB2 IGF1R MAGEL2 MTNR1A MTNR1B NDN NISCH PIK3CA PIK3R1 PRKCZ PTPN11 PTPN6 RNF41 SOCS6 SOCS7 YWHAG	12 interacting genes: DAB1 EGFR GRB2 IRS2 IRS4 NCK1 PIK3R1 PIK3R2 PLCG1 SORBS3 TUBA1A TUBB4B
Entrez ID		8471	30837
HPRD ID		04620	12299
Ensembl ID		ENSG00000133124	ENSG00000274211
Uniprot IDs		O14654	O14512
PDB IDs
Enriched GO Terms of Interacting Partners?
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