SOCS7 and IRS4

Number of citations of the paper that reports this interaction (PubMedID 12052866)
38

		SOCS7	IRS4
Description		suppressor of cytokine signaling 7	insulin receptor substrate 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane Phosphatidylinositol 3-kinase Complex	Cytosol Plasma Membrane
	Molecular Function	Protein Binding SH3 Domain Binding 1-phosphatidylinositol-3-kinase Regulator Activity	SH3/SH2 Adaptor Activity Insulin Receptor Binding Protein Binding Phosphatidylinositol 3-kinase Binding
	Biological Process	Biological_process Negative Regulation Of Signal Transduction Protein Ubiquitination Intracellular Signal Transduction Regulation Of Growth Regulation Of Phosphatidylinositol 3-kinase Activity Phosphatidylinositol Phosphorylation	Signal Transduction Insulin Receptor Signaling Pathway Positive Regulation Of Signal Transduction
Pathways			IRS-related events triggered by IGF1R
Drugs
Diseases
GWAS		Ovarian cancer ( 23535730)
Interacting Genes		12 interacting genes: DAB1 EGFR GRB2 IRS2 IRS4 NCK1 PIK3R1 PIK3R2 PLCG1 SORBS3 TUBA1A TUBB4B	21 interacting genes: CRK CRKL CSNK1G2 EGFR ERBB2 GRB2 IGF1R MAGEL2 MTNR1A MTNR1B NDN NISCH PIK3CA PIK3R1 PRKCZ PTPN11 PTPN6 RNF41 SOCS6 SOCS7 YWHAG
Entrez ID		30837	8471
HPRD ID		12299	04620
Ensembl ID		ENSG00000274211	ENSG00000133124
Uniprot IDs		O14512	O14654
PDB IDs
Enriched GO Terms of Interacting Partners?
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