TRIM63 and UBE2V2

Number of citations of the paper that reports this interaction (PubMedID 23695783)
9

Data Source:
BioGRID (pull down)

		TRIM63	UBE2V2
Description		tripartite motif containing 63	ubiquitin conjugating enzyme E2 V2
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GO Annotations	Cellular Component	Nucleus Cytoplasm Microtubule Z Disc M Band	Nucleus Nucleoplasm Cytoplasm UBC13-MMS2 Complex Extracellular Exosome
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Titin Binding	Protein Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	Muscle Contraction Signal Transduction Negative Regulation Of Cardiac Muscle Hypertrophy Skeletal Muscle Atrophy Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Protein Ubiquitination Response To Glucocorticoid Response To Interleukin-1	Protein Polyubiquitination DNA Double-strand Break Processing Regulation Of DNA Repair Postreplication Repair Double-strand Break Repair Via Nonhomologous End Joining Protein Ubiquitination Error-free Postreplication DNA Repair Protein K63-linked Ubiquitination
Pathways		FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes Antigen processing: Ubiquitination & Proteasome degradation	Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Nonhomologous End-Joining (NHEJ) Processing of DNA double-strand break ends Formation of Incision Complex in GG-NER G2/M DNA damage checkpoint E3 ubiquitin ligases ubiquitinate target proteins Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Height ( 31562340)
Interacting Genes		93 interacting genes: ACTA1 AK1 AKR7A2 ALDOA ANKRD1 APP ATP5F1B ATXN3 ATXN3L BAP1 CKB CKM DCAF6 DES EEF1G EHHADH EIF3E ENO3 ESPL1 FHL2 FLNC GFM1 GMEB1 HIBADH HSPD1 JOSD1 LMCD1 MRPL19 MRPL41 MYBPC1 MYBPC3 MYH6 MYL2 MYOT MYOZ1 NDUFA1 NEB NEBL NOMO1 NRAP OTUB1 OTUB2 PDHB PDK4 PIAS1 PIAS2 PIAS3 PKM PSMD4 PYGM SENP2 SENP3 SQSTM1 SRF STAM SUMO2 TCAP THRA TNNC1 TNNI1 TNNI2 TNNI3 TNNT1 TNNT3 TRIM54 TRIM55 TTN UBE2D1 UBE2D2 UBE2D3 UBE2E3 UBE2I UBE2J1 UBE2K UBE2N UBE2U UBE2V2 UCHL1 UCHL3 UCHL5 UQCRC1 USP13 USP15 USP2 USP21 USP28 USP33 USP4 USP5 USP7 USP8 UXT YOD1	33 interacting genes: BCL10 DZIP3 EGFR HLTF IGSF21 LNX1 LRIF1 MALT1 MKRN3 MOB4 MUL1 OTUB1 RC3H1 RC3H2 RFFL RNF144A RNF2 RNF8 SHPRH SIAH1 SIAH2 STUB1 SUV39H2 TP53 TRAF2 TRIM21 TRIM5 TRIM54 TRIM63 UBC UBE2N XIAP ZNRF1
Entrez ID		84676	7336
HPRD ID		05843	04300
Ensembl ID		ENSG00000158022	ENSG00000169139
Uniprot IDs		Q969Q1	A0M8W4 Q15819
PDB IDs		2D8U 3DDT 4M3L	1J74 1J7D 1ZGU 3VON 4NR3 4NRG 4NRI 4ONL 4ONM 4ONN 4ORH 5AIT
Enriched GO Terms of Interacting Partners?
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