UBE2V2 and HLTF

Number of citations of the paper that reports this interaction (PubMedID 18316726)
85

Data Source:
BioGRID (pull down, affinity chromatography technology, affinity chromatography technology, pull down)

		UBE2V2	HLTF
Description		ubiquitin conjugating enzyme E2 V2	helicase like transcription factor
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm UBC13-MMS2 Complex Extracellular Exosome	Nucleus Nucleoplasm Nucleolus Cytosol Membrane
	Molecular Function	Protein Binding Ubiquitin Conjugating Enzyme Activity	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding RNA Binding Helicase Activity Protein Binding ATP Binding DNA-dependent ATPase Activity Zinc Ion Binding Ubiquitin Protein Ligase Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Polyubiquitination DNA Double-strand Break Processing Regulation Of DNA Repair Postreplication Repair Double-strand Break Repair Via Nonhomologous End Joining Protein Ubiquitination Error-free Postreplication DNA Repair Protein K63-linked Ubiquitination	Chromatin Organization Regulation Of Transcription, DNA-templated Protein Ubiquitination Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Nonhomologous End-Joining (NHEJ) Processing of DNA double-strand break ends Formation of Incision Complex in GG-NER G2/M DNA damage checkpoint E3 ubiquitin ligases ubiquitinate target proteins Antigen processing: Ubiquitination & Proteasome degradation	E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS		Height ( 31562340)
Interacting Genes		33 interacting genes: BCL10 DZIP3 EGFR HLTF IGSF21 LNX1 LRIF1 MALT1 MKRN3 MOB4 MUL1 OTUB1 RC3H1 RC3H2 RFFL RNF144A RNF2 RNF8 SHPRH SIAH1 SIAH2 STUB1 SUV39H2 TP53 TRAF2 TRIM21 TRIM5 TRIM54 TRIM63 UBC UBE2N XIAP ZNRF1	14 interacting genes: CDK9 DCAF1 EEF1G EWSR1 HSPA8 PCNA SP1 SP3 SULT1C2 UBC UBE2A UBE2V2 UBE2Z WBP4
Entrez ID		7336	6596
HPRD ID		04300	04461
Ensembl ID		ENSG00000169139	ENSG00000071794
Uniprot IDs		A0M8W4 Q15819	A0A0C4DGA6 A8K5B6 Q05BZ6 Q14527
PDB IDs		1J74 1J7D 1ZGU 3VON 4NR3 4NRG 4NRI 4ONL 4ONM 4ONN 4ORH 5AIT	2MZN 4HRE 4HRH 4S0N 4XZF 4XZG 5BNH 5K5F
Enriched GO Terms of Interacting Partners?
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