VPS25 and SNF8

Number of citations of the paper that reports this interaction (PubMedID 14505570)
373

Data Source:
BioGRID (biochemical, two hybrid)
HPRD (two hybrid)

		VPS25	SNF8
Description		vacuolar protein sorting 25 homolog	SNF8 subunit of ESCRT-II
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GO Annotations	Cellular Component	ESCRT II Complex Nucleus Nucleoplasm Cytoplasm Cytosol Endosome Membrane Extracellular Exosome	ESCRT II Complex Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm Cytosol Plasma Membrane Endosome Membrane Membrane Late Endosome Membrane Perinuclear Region Of Cytoplasm Recycling Endosome Extracellular Exosome
	Molecular Function	Structural Molecule Activity Protein Binding Protein Homodimerization Activity Protein N-terminus Binding	Protein Binding Protein C-terminus Binding Transcription Factor Binding Channel Regulator Activity Protein Homodimerization Activity Protein N-terminus Binding
	Biological Process	Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Endosomal Transport Macroautophagy Multivesicular Body Assembly Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression Regulation Of Multivesicular Body Size Involved In Endosome Transport Endosomal Transport Macroautophagy Endocytic Recycling Multivesicular Body Assembly Regulation Of Protein Catabolic Process Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of MAP Kinase Activity Early Endosome To Late Endosome Transport Positive Regulation Of Protein Catabolic Process Regulation Of Protein Complex Stability Multivesicular Body Sorting Pathway Positive Regulation Of Exosomal Secretion Regulation Of Viral Budding Via Host ESCRT Complex
Pathways		Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events	Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events
Drugs
Diseases
GWAS			Coronary heart disease ( 21378990) Type 2 diabetes ( 29358691)
Interacting Genes		11 interacting genes: APIP BEND5 CHMP6 CRLF3 DCAKD REL RHOXF2 SNF8 SPRY2 TRIM27 VPS36	17 interacting genes: ADORA1 CHMP6 DVL2 ELL GOLGA2 HMOX1 KDM1A NIF3L1 PRMT6 RILP SUV39H2 TRIM54 TSG101 VAC14 VPS25 VPS36 YWHAE
Entrez ID		84313	11267
HPRD ID		14396	16847
Ensembl ID		ENSG00000131475	ENSG00000159210
Uniprot IDs		A0A024R1X3 Q9BRG1	Q96H20
PDB IDs		2ZME 3CUQ 3HTU	2ZME 3CUQ
Enriched GO Terms of Interacting Partners?
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