SNF8 and SUV39H2

Number of citations of the paper that reports this interaction (PubMedID 23455924)
38

Data Source:
BioGRID (two hybrid)

		SNF8	SUV39H2
Description		SNF8 subunit of ESCRT-II	suppressor of variegation 3-9 homolog 2
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GO Annotations	Cellular Component	ESCRT II Complex Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm Cytosol Plasma Membrane Endosome Membrane Membrane Late Endosome Membrane Perinuclear Region Of Cytoplasm Recycling Endosome Extracellular Exosome	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm
	Molecular Function	Protein Binding Protein C-terminus Binding Transcription Factor Binding Channel Regulator Activity Protein Homodimerization Activity Protein N-terminus Binding	Transcription Regulatory Region Sequence-specific DNA Binding Protein Binding Zinc Ion Binding Histone Methyltransferase Activity (H3-K9 Specific) S-adenosyl-L-methionine Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression Regulation Of Multivesicular Body Size Involved In Endosome Transport Endosomal Transport Macroautophagy Endocytic Recycling Multivesicular Body Assembly Regulation Of Protein Catabolic Process Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of MAP Kinase Activity Early Endosome To Late Endosome Transport Positive Regulation Of Protein Catabolic Process Regulation Of Protein Complex Stability Multivesicular Body Sorting Pathway Positive Regulation Of Exosomal Secretion Regulation Of Viral Budding Via Host ESCRT Complex	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Assembly Or Disassembly Chromatin Remodeling Cell Cycle Cell Differentiation Histone Lysine Methylation Histone H3-K9 Dimethylation Histone H3-K9 Trimethylation Negative Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Rhythmic Process Cellular Response To Hypoxia
Pathways		Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events	PKMTs methylate histone lysines
Drugs
Diseases
GWAS		Coronary heart disease ( 21378990) Type 2 diabetes ( 29358691)	Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		17 interacting genes: ADORA1 CHMP6 DVL2 ELL GOLGA2 HMOX1 KDM1A NIF3L1 PRMT6 RILP SUV39H2 TRIM54 TSG101 VAC14 VPS25 VPS36 YWHAE	40 interacting genes: AKAP9 APPL2 AR BLZF1 C8orf74 CBX7 CCDC151 CDCA4 CEP70 CFAP100 CGGBP1 EWSR1 FAM20C GSTCD ID2 KCTD17 KLF3 KLHDC4 LCA5L LNX1 LRIF1 MAGEA11 MCM3AP MRFAP1 MTF2 MYL12A NME4 PHF19 PNMA1 POLR3F RAB3IP RASSF1 SHC1 SMAD5 SNF8 UBE2V2 WIZ ZNF212 ZNF557 ZNF57
Entrez ID		11267	79723
HPRD ID		16847	07580
Ensembl ID		ENSG00000159210	ENSG00000152455
Uniprot IDs		Q96H20	Q9H5I1
PDB IDs		2ZME 3CUQ	2R3A 6P0R
Enriched GO Terms of Interacting Partners?
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