VPS25 and CHMP6

Number of citations of the paper that reports this interaction (PubMedID 14505570)
373

Data Source:
BioGRID (affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, pull down)
HPRD (in vivo, in vitro, two hybrid)

		VPS25	CHMP6
Description		vacuolar protein sorting 25 homolog	charged multivesicular body protein 6
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GO Annotations	Cellular Component	ESCRT II Complex Nucleus Nucleoplasm Cytoplasm Cytosol Endosome Membrane Extracellular Exosome	ESCRT III Complex Cell Cytosol Endosome Membrane Membrane Late Endosome Membrane Extracellular Exosome
	Molecular Function	Structural Molecule Activity Protein Binding Protein Homodimerization Activity Protein N-terminus Binding	Protein Binding Protein-containing Complex Binding Protein N-terminus Binding
	Biological Process	Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Endosomal Transport Macroautophagy Multivesicular Body Assembly Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway	Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Protein Transport Endosomal Transport Macroautophagy Viral Life Cycle Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Regulation Of Protein Catabolic Process Midbody Abscission Regulation Of Exosomal Secretion ESCRT III Complex Assembly
Pathways		Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events	Budding and maturation of HIV virion Macroautophagy Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III
Drugs
Diseases
GWAS
Interacting Genes		11 interacting genes: APIP BEND5 CHMP6 CRLF3 DCAKD REL RHOXF2 SNF8 SPRY2 TRIM27 VPS36	8 interacting genes: CHMP4A CHMP4B ELOF1 METTL9 RTN4 SNF8 VPS25 VPS36
Entrez ID		84313	79643
HPRD ID		14396	08564
Ensembl ID		ENSG00000131475	ENSG00000176108
Uniprot IDs		A0A024R1X3 Q9BRG1	Q96FZ7
PDB IDs		2ZME 3CUQ 3HTU	2K3W 3HTU
Enriched GO Terms of Interacting Partners?
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