VPS25 and CRLF3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		VPS25	CRLF3
Description		vacuolar protein sorting 25 homolog	cytokine receptor like factor 3
Image			No pdb structure
GO Annotations	Cellular Component	ESCRT II Complex Nucleus Nucleoplasm Cytoplasm Cytosol Endosome Membrane Extracellular Exosome	Nucleus Cytoplasm Cytosol Plasma Membrane
	Molecular Function	Structural Molecule Activity Protein Binding Protein Homodimerization Activity Protein N-terminus Binding	DNA Binding Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Endosomal Transport Macroautophagy Multivesicular Body Assembly Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway	G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Growth Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of JAK-STAT Cascade Positive Regulation Of Cell Cycle Arrest
Pathways		Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events
Drugs
Diseases
GWAS			Birth weight ( 27680694) Chronic obstructive pulmonary disease ( 30804561) Height ( 28552196 18391951) Mean corpuscular hemoglobin ( 29403010)
Interacting Genes		11 interacting genes: APIP BEND5 CHMP6 CRLF3 DCAKD REL RHOXF2 SNF8 SPRY2 TRIM27 VPS36	6 interacting genes: APPL2 KDM1A LGALS14 RBM14 TMEM97 VPS25
Entrez ID		84313	51379
HPRD ID		14396	16757
Ensembl ID		ENSG00000131475	ENSG00000176390
Uniprot IDs		A0A024R1X3 Q9BRG1	Q8IUI8
PDB IDs		2ZME 3CUQ 3HTU
Enriched GO Terms of Interacting Partners?
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