PRAM1 and SKAP2

Number of citations of the paper that reports this interaction (PubMedID 11301322)
12

Data Source:
HPRD (in vivo)

		PRAM1	SKAP2
Description		PML-RARA regulated adaptor molecule 1	src kinase associated phosphoprotein 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Protein-containing Complex	Nucleoplasm Cytoplasm Cytosol Plasma Membrane
	Molecular Function	Protein Binding Lipid Binding Protein Kinase Binding	SH3/SH2 Adaptor Activity Protein Binding
	Biological Process	Integrin-mediated Signaling Pathway Regulation Of Neutrophil Degranulation T Cell Receptor Signaling Pathway Protein Localization To Plasma Membrane	Signal Transduction Negative Regulation Of Cell Proliferation Positive Regulation Of Signal Transduction B Cell Activation Protein-containing Complex Assembly
Pathways			Signal regulatory protein family interactions
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Height ( 18391951)	Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Chronic venous disease ( 28374850) Erosive tooth wear (severe vs non-severe) ( 29898447) Erosive tooth wear (severe vs none or mild) ( 29898447) FEV1 ( 30804560) Lung function (FVC) ( 30804560) Macular thickness ( 30535121) Peak expiratory flow ( 30804560) Small cell lung carcinoma ( 28604730) Systemic lupus erythematosus ( 28714469)
Interacting Genes		19 interacting genes: A2M ABI2 APOE APP CCDC57 CDC37 FXR2 KRT40 LCP2 LYN MAST1 MXD1 NEK6 PSEN1 RNF32 SKAP1 SKAP2 TRIM27 UBE2E2	19 interacting genes: APP BLK FAM102A FASLG FGR FRK FYB1 FYN HCK KHDRBS1 LCK LYN NCK2 PRAM1 PTK2B SRC SRMS TGFBR1 YES1
Entrez ID		84106	8935
HPRD ID		05926	05558
Ensembl ID		ENSG00000133246	ENSG00000005020
Uniprot IDs		Q96QH2	B7Z5R3 O75563
PDB IDs			3OMH
Enriched GO Terms of Interacting Partners?
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