SKAP2 and SRMS

Number of citations of the paper that reports this interaction (PubMedID 29568343)
1

Data Source:
BioGRID (protein complementation assay)

		SKAP2	SRMS
Description		src kinase associated phosphoprotein 2	src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Plasma Membrane	Cytoplasm Cytosol Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
	Molecular Function	SH3/SH2 Adaptor Activity Protein Binding	Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Signaling Receptor Binding Protein Binding ATP Binding
	Biological Process	Signal Transduction Negative Regulation Of Cell Proliferation Positive Regulation Of Signal Transduction B Cell Activation Protein-containing Complex Assembly	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Negative Regulation Of Signal Transduction Cell Migration Peptidyl-tyrosine Phosphorylation Cell Differentiation Peptidyl-tyrosine Autophosphorylation Regulation Of Cell Proliferation
Pathways		Signal regulatory protein family interactions	PTK6 Down-Regulation
Drugs
Diseases
GWAS		Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Chronic venous disease ( 28374850) Erosive tooth wear (severe vs non-severe) ( 29898447) Erosive tooth wear (severe vs none or mild) ( 29898447) FEV1 ( 30804560) Lung function (FVC) ( 30804560) Macular thickness ( 30535121) Peak expiratory flow ( 30804560) Small cell lung carcinoma ( 28604730) Systemic lupus erythematosus ( 28714469)	Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Prostate cancer ( 23535732)
Interacting Genes		19 interacting genes: APP BLK FAM102A FASLG FGR FRK FYB1 FYN HCK KHDRBS1 LCK LYN NCK2 PRAM1 PTK2B SRC SRMS TGFBR1 YES1	4 interacting genes: DUXAP9 NEDD4 NEDD4L SKAP2
Entrez ID		8935	6725
HPRD ID		05558	10250
Ensembl ID		ENSG00000005020	ENSG00000125508
Uniprot IDs		B7Z5R3 O75563	Q9H3Y6
PDB IDs		3OMH
Enriched GO Terms of Interacting Partners?
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