ENKD1 and PHC2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		ENKD1	PHC2
Description		enkurin domain containing 1	polyhomeotic homolog 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasmic Microtubule Microtubule Cytoskeleton	Heterochromatin Nucleus Nucleoplasm PcG Protein Complex PRC1 Complex
	Molecular Function	Protein Binding	DNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding
	Biological Process		Multicellular Organism Development Spermatogenesis
Pathways			Oxidative Stress Induced Senescence SUMOylation of DNA damage response and repair proteins SUMOylation of transcription cofactors SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA methylation proteins RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Regulation of PTEN gene transcription Regulation of PTEN gene transcription
Drugs
Diseases
GWAS		Schizophrenia ( 25056061 29483656)	Adventurousness ( 30643258) Blood urea nitrogen levels ( 31152163 29403010) General risk tolerance (MTAG) ( 30643258) Pulse pressure ( 30224653) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking status (ever vs never smokers) ( 30643258) Urinary albumin excretion ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189)
Interacting Genes		37 interacting genes: APP BEGAIN CALCOCO2 CBY2 CCDC102B CCDC136 CCDC85B CDR2 CEP70 DGCR6 DVL2 DVL3 FAM102A KRTAP10-5 MDFI MIPOL1 MKRN3 NBPF22P NEFL PDLIM7 PHC2 PLSCR1 PNMA1 PNMA2 PPP1CC RAD54B RBPMS SPAG5 SPSB3 STAC3 TRAF2 TRGV7 TRIM54 TSC22D4 UBXN11 YWHAE ZBTB14	71 interacting genes: AEN AFG3L2 AP1M1 BMI1 BSDC1 BYSL C1orf109 CARD9 CBX2 CRK CRKL CSNK2B DRG1 ENKD1 FAM124A FAM13C FAM161A FAM74A1 FAM74A4 FHL3 GFI1B GRB2 H3-4 KAT5 KBTBD7 KDM1A KIFC3 L3MBTL3 LMO1 LMO2 LMO3 MAB21L3 MAGEB6 MAPK14 MAPK6 MAPKAPK2 MCM2 MCRS1 MFAP1 MORF4L2 NCK1 PCGF2 PCGF3 PCGF5 PHC1 PLK1 POLR2L PPP1R16B PRKAA1 PRPF3 PRPF31 RBM39 RNF2 RPL7 RWDD2B SCMH1 SDCBP SFMBT1 SIAH1 SMAD3 SPATC1L SSX2IP SYT16 TAB1 THAP7 TMEM70 TRIM41 ZBTB24 ZGPAT ZMAT2 ZNF417
Entrez ID		84080	1912
HPRD ID		13151	10340
Ensembl ID		ENSG00000124074	ENSG00000134686
Uniprot IDs		Q9H0I2	A0A0A0MSI2 Q8IXK0
PDB IDs
Enriched GO Terms of Interacting Partners?
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