MAD1L1 and MAD2L1

  • Number of citations of the paper that reports this interaction (PubMedID 11459826)
  • 48
  • Data Source:
  • HPRD (in vitro)

MAD1L1

MAD2L1

Description mitotic arrest deficient 1 like 1 mitotic arrest deficient 2 like 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to drug ( 30420678)
  • Age at first sexual intercourse ( 27089180)
  • Alcohol consumption (drinks per week) ( 30643258)
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Anthropometric traits (multi-trait analysis) ( 30166351)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Bipolar disorder ( 28115744 21926972 27329760)
  • Bitter alcoholic beverage consumption ( 31046077)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Coronary artery disease ( 29212778)
  • Dimensional psychopathology (Social) ( 29496196)
  • Gastroesophageal reflux disease ( 31527586)
  • General factor of neuroticism ( 30867560)
  • Hand grip strength ( 29691431)
  • Longevity ( 20834067)
  • Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269)
  • Number of sexual partners ( 30643258)
  • Prostate cancer ( 29892016)
  • Prostate cancer (advanced) ( 29892016)
  • Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814)
  • Risk-taking tendency (4-domain principal component model) ( 30643258)
  • Rosacea symptom severity ( 29771307)
  • Schizophrenia ( 28991256 29483656 22688191 30285260 23974872)
  • Schizophrenia or bipolar disorder ( 24280982)
  • Schizophrenia, schizoaffective disorder or bipolar disorder ( 24166486)
  • Sleep duration (short sleep) ( 30846698)
  • Smoking status (ever vs never smokers) ( 30643258)
  • Superior frontal gyrus volume ( 31530798)
  • Superior temporal gyrus volume ( 31530798)
  • Systolic blood pressure ( 30578418)
  • Testicular germ cell tumor ( 28604728 28604732 23666239)
  • Coronary artery disease ( 28714974)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • F-cell distribution in sickle cell anaemia ( 21326311)
  • HIV-1 viral setpoint ( 22174851)
  • Loneliness (multivariate analysis) ( 27629369)
Interacting Genes 40 interacting genes: ALOX5 AMOTL2 BIRC2 CCHCR1 COIL CWF19L2 FAM131C HAUS1 HDAC1 HDAC2 LGALSL MAD2L1 MAX MFAP1 MLX NDC80 NEBL NEK2 NINL NONO PML PSMA1 RNF8 SIN3A SIN3B SPATA2 SUPT5H TEX11 TPM1 TPM3 TPR TRIM29 TSC22D3 TSHZ3 TUBGCP4 UBC UBTF USP15 YJU2 ZSCAN32 23 interacting genes: ADAM17 ANAPC2 APP CCNA2 CDC16 CDC20 CDC27 CSF2RB ESR2 H3C1 INSR KEAP1 MAD1L1 MAD2L1BP MAD2L2 MBL2 NDC80 RABAC1 REV3L SDCBP TRIP13 TSC22D4 UBD
Entrez ID 8379 4085
HPRD ID 04065 03274
Ensembl ID ENSG00000002822 ENSG00000164109
Uniprot IDs Q9Y6D9 Q13257
PDB IDs 1GO4 4DZO 1DUJ 1GO4 1KLQ 1S2H 2QYF 2V64 2VFX 3GMH 5KHU 5LCW 6F0X
Enriched GO Terms of Interacting Partners?
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