MAD2L1 and ADAM17

  • Number of citations of the paper that reports this interaction (PubMedID 10527948)
  • 19
  • Data Source:
  • HPRD (two hybrid, in vitro)

MAD2L1

ADAM17

Description mitotic arrest deficient 2 like 1 ADAM metallopeptidase domain 17
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Coronary artery disease ( 28714974)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • F-cell distribution in sickle cell anaemia ( 21326311)
  • HIV-1 viral setpoint ( 22174851)
  • Loneliness (multivariate analysis) ( 27629369)
Interacting Genes 23 interacting genes: ADAM17 ANAPC2 APP CCNA2 CDC16 CDC20 CDC27 CSF2RB ESR2 H3C1 INSR KEAP1 MAD1L1 MAD2L1BP MAD2L2 MBL2 NDC80 RABAC1 REV3L SDCBP TRIP13 TSC22D4 UBD 15 interacting genes: DLG1 ERBB4 FHL2 MAD2L1 MAD2L2 NOTCH1 PTPN3 SH3D19 TGFA TIMP3 TNF TNFRSF1A TNFRSF1B TNFSF11 YIF1A
Entrez ID 4085 6868
HPRD ID 03274 04703
Ensembl ID ENSG00000164109 ENSG00000151694
Uniprot IDs Q13257 B2RNB2 P78536
PDB IDs 1DUJ 1GO4 1KLQ 1S2H 2QYF 2V64 2VFX 3GMH 5KHU 5LCW 6F0X 1BKC 1ZXC 2A8H 2DDF 2FV5 2FV9 2I47 2M2F 2OI0 3B92 3CKI 3E8R 3EDZ 3EWJ 3G42 3KMC 3KME 3L0T 3L0V 3LE9 3LEA 3LGP 3O64
Enriched GO Terms of Interacting Partners?
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