TXNDC5 and TRIM42

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TXNDC5	TRIM42
Description		thioredoxin domain containing 5	tripartite motif containing 42
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cell Endoplasmic Reticulum Endoplasmic Reticulum Lumen Azurophil Granule Lumen Lysosomal Lumen Extracellular Exosome
	Molecular Function	Protein Binding Isomerase Activity	Protein Binding Zinc Ion Binding
	Biological Process	Negative Regulation Of Apoptotic Process Apoptotic Cell Clearance Neutrophil Degranulation Cell Redox Homeostasis
Pathways		Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis Neutrophil degranulation
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) High chromosomal aberration frequency (chromatid type) ( 31586183)	Bipolar disorder (body mass index interaction) ( 24322204) Refractive astigmatism ( 25367360)
Interacting Genes		26 interacting genes: APP AR BLZF1 EDEM3 EFEMP1 FLACC1 GMPPB KRT38 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-12 KRTAP4-2 LHX4 MGAT5B NOTCH2NLA PJA1 PRDX2 RAB3IP SPRY2 TRIM23 TRIM42 TRIP6	64 interacting genes: ADAMTSL4 ARMC7 ARNT2 ARRDC3 AXIN1 BEX2 C1orf109 CARD9 CBY2 CCDC33 CDCA7L CEP70 EFHC2 EMD GLI1 GLRX3 GLYCTK GOLGA2 HOXA1 IHO1 IKZF3 IQUB KCTD9 KLHL38 KRT13 KRT15 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP26-1 KRTAP3-2 KRTAP4-2 L3MBTL2 LONRF1 LZTS2 MAGOHB MEOX2 MFAP1 MID2 MTUS2 MVP NOTCH2NLA PLSCR1 PNMA1 PSMA1 PSMD9 PTGER3 RAMAC RCOR3 RUNX1T1 SCNM1 SSX2IP STK16 TASOR2 TRAF1 TRAF2 TRAPPC2B TRIM23 TRIM27 TXNDC5 VPS37A YWHAQ ZBTB1
Entrez ID		81567	287015
HPRD ID		18249	15559
Ensembl ID		ENSG00000239264	ENSG00000155890
Uniprot IDs		A0A024QZV0 Q8NBS9	Q8IWZ5
PDB IDs		2DIZ 3UJ1 3UVT 3WGD 3WGE 3WGX
Enriched GO Terms of Interacting Partners?
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