TXNDC5 and KRT38

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TXNDC5	KRT38
Description		thioredoxin domain containing 5	keratin 38
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cell Endoplasmic Reticulum Endoplasmic Reticulum Lumen Azurophil Granule Lumen Lysosomal Lumen Extracellular Exosome	Cytosol Intermediate Filament Extracellular Exosome
	Molecular Function	Protein Binding Isomerase Activity	Structural Molecule Activity Protein Binding
	Biological Process	Negative Regulation Of Apoptotic Process Apoptotic Cell Clearance Neutrophil Degranulation Cell Redox Homeostasis	Keratinization Cornification
Pathways		Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis Neutrophil degranulation	Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) High chromosomal aberration frequency (chromatid type) ( 31586183)
Interacting Genes		26 interacting genes: APP AR BLZF1 EDEM3 EFEMP1 FLACC1 GMPPB KRT38 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-12 KRTAP4-2 LHX4 MGAT5B NOTCH2NLA PJA1 PRDX2 RAB3IP SPRY2 TRIM23 TRIM42 TRIP6	46 interacting genes: AMOTL2 ANKRD36BP1 BEX2 C19orf57 C1orf216 CCDC146 CD300A CEP57L1 FAM90A1 GLRX3 GNG10 HAUS1 HDAC4 HGS HMG20B HOXA1 KDM1A KLHL38 KRT2 KRT4 KRT5 KRT6A KRT6B KRT6C KRT71 KRT79 KRT8 KRT81 KRT83 LHX4 MAGEB4 PIK3R2 PIN1 PSMA1 PSMC5 PTGER3 RHPN1-AS1 SCNM1 TXLNA TXLNB TXNDC5 USHBP1 ZFYVE21 ZNF20 ZNF417 ZNF587
Entrez ID		81567	8687
HPRD ID		18249	05176
Ensembl ID		ENSG00000239264	ENSG00000171360
Uniprot IDs		A0A024QZV0 Q8NBS9	O76015
PDB IDs		2DIZ 3UJ1 3UVT 3WGD 3WGE 3WGX
Enriched GO Terms of Interacting Partners?
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