FXR1 and ERG28

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		FXR1	ERG28
Description		FMR1 autosomal homolog 1	ergosterol biosynthesis 28 homolog
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Cytosol Polysome Postsynaptic Density Membrane Axon Growth Cone Ribonucleoprotein Granule Cytoplasmic Ribonucleoprotein Granule Neuronal Cell Body Costamere Dendritic Spine Dendritic Spine Neck Perinuclear Region Of Cytoplasm Presynapse Glutamatergic Synapse Dendritic Filopodium	Integral Component Of Membrane Transport Vesicle
	Molecular Function	RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding RNA Strand Annealing Activity Protein Homodimerization Activity Translation Regulator Activity Protein Heterodimerization Activity	Molecular_function Protein Binding, Bridging
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of Protein Phosphorylation Apoptotic Process Muscle Organ Development Negative Regulation Of Translation Cell Differentiation Regulation Of MRNA Stability Positive Regulation Of Translation Regulation Of Filopodium Assembly Positive Regulation Of Gene Silencing By MiRNA Positive Regulation Of Response To DNA Damage Stimulus	Biological_process
Pathways		Signaling by BRAF and RAF fusions
Drugs
Diseases
GWAS		Bipolar disorder and eating disorder ( 26433762) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Eating disorder in bipolar disorder ( 26433762) Metabolite levels ( 23823483) Schizophrenia ( 25056061 19571811 29483656 30285260)
Interacting Genes		13 interacting genes: CEP126 CRMP1 CSNK2A1 CYFIP2 ERG28 FBXO4 FMR1 FXR2 GBP2 HSPB1 LRIF1 LUC7L2 PRSS23	66 interacting genes: ALDH2 ANXA1 ANXA7 AQP2 BAIAP2 BID BTBD2 CCDC106 CCL18 CDC42 CDK5RAP2 CELF3 CLN8 COX17 CRADD CREB1 CREB3 CSTF2 DYNLL1 FAS FCGR2B FXR1 GADD45A GSK3B HMGB1 HNRNPH3 HNRNPUL1 HSPE1 HYLS1 KLHL20 LMNA LSM2 MAPK8IP2 MPHOSPH6 MRPL38 MRPS12 MTNR1B NAT9 NDUFA4L2 NR1H2 NSF PAFAH1B3 PCDHA4 PEX2 PFN1 PHYHIP POLE2 POLR2C POLR3F PPP1R8 PQBP1 RAB27A RPS6KA6 S100A8 SAT1 SEPHS1 SERPINB9 SNRPB SNRPG SULT1E1 TFG TK1 TSC22D1 TTR ZFP64 ZNF24
Entrez ID		8087	11161
HPRD ID		02892	05201
Ensembl ID		ENSG00000114416	ENSG00000133935
Uniprot IDs		A0A0F7KYT8 A0A0F7L1S3 P51114	Q6FII3 Q86TW5 Q9UKR5
PDB IDs		2CPQ 3KUF 3O8V
Enriched GO Terms of Interacting Partners?
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