FXR1 and LUC7L2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		FXR1	LUC7L2
Description		FMR1 autosomal homolog 1	LUC7 like 2, pre-mRNA splicing factor
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Cytosol Polysome Postsynaptic Density Membrane Axon Growth Cone Ribonucleoprotein Granule Cytoplasmic Ribonucleoprotein Granule Neuronal Cell Body Costamere Dendritic Spine Dendritic Spine Neck Perinuclear Region Of Cytoplasm Presynapse Glutamatergic Synapse Dendritic Filopodium	U1 SnRNP Nuclear Speck U2-type Prespliceosome
	Molecular Function	RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding RNA Strand Annealing Activity Protein Homodimerization Activity Translation Regulator Activity Protein Heterodimerization Activity	RNA Binding MRNA Binding Protein Binding Enzyme Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of Protein Phosphorylation Apoptotic Process Muscle Organ Development Negative Regulation Of Translation Cell Differentiation Regulation Of MRNA Stability Positive Regulation Of Translation Regulation Of Filopodium Assembly Positive Regulation Of Gene Silencing By MiRNA Positive Regulation Of Response To DNA Damage Stimulus	MRNA Splice Site Selection
Pathways		Signaling by BRAF and RAF fusions
Drugs
Diseases
GWAS		Bipolar disorder and eating disorder ( 26433762) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Eating disorder in bipolar disorder ( 26433762) Metabolite levels ( 23823483) Schizophrenia ( 25056061 19571811 29483656 30285260)	Diisocyanate-induced asthma ( 25918132)
Interacting Genes		13 interacting genes: CEP126 CRMP1 CSNK2A1 CYFIP2 ERG28 FBXO4 FMR1 FXR2 GBP2 HSPB1 LRIF1 LUC7L2 PRSS23	51 interacting genes: AIMP2 ALB ANTKMT APP APPBP2 ATF7IP ATRX CADPS CDC37 CDK4 CDK5RAP2 CEP126 CHD3 EXOC1 FXR1 GADD45G GSK3B HAP1 HDHD2 IKBKG ITPRID2 KLHL20 LPL MAN2A2 MAP1LC3B NAP1L5 NASP NAT9 NDEL1 NDUFA4L2 NEDD4 NFYA NKAP NSF NUTF2 OFD1 PABPC4 PDPK1 PEA15 PIK3R3 PTCD3 PTN SAT1 SETDB1 SRSF6 SVIL ULK2 UNC119 WASHC3 YWHAG ZCCHC10
Entrez ID		8087	51631
HPRD ID		02892	17456
Ensembl ID		ENSG00000114416	ENSG00000146963
Uniprot IDs		A0A0F7KYT8 A0A0F7L1S3 P51114	Q9Y383
PDB IDs		2CPQ 3KUF 3O8V
Enriched GO Terms of Interacting Partners?
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