ERG28 and PEX2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ERG28	PEX2
Description		ergosterol biosynthesis 28 homolog	peroxisomal biogenesis factor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane Transport Vesicle	Peroxisomal Membrane Integral Component Of Peroxisomal Membrane Membrane Cdc73/Paf1 Complex
	Molecular Function	Molecular_function Protein Binding, Bridging	Protein Binding Metal Ion Binding
	Biological Process	Biological_process	Very Long-chain Fatty Acid Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Protein Targeting To Peroxisome Fatty Acid Beta-oxidation Peroxisome Organization Protein Import Into Peroxisome Matrix Protein Ubiquitination Protein Destabilization Negative Regulation Of Fibroblast Proliferation Negative Regulation Of Epithelial Cell Proliferation
Pathways			E3 ubiquitin ligases ubiquitinate target proteins Peroxisomal protein import Peroxisomal protein import Class I peroxisomal membrane protein import
Drugs
Diseases			Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS			Fasting plasma glucose ( 31170924) Height ( 20881960 31562340) Infant length ( 25281659) Menarche (age at onset) ( 27182965 25231870) Nicotine dependence ( 28440896) Systolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415)
Interacting Genes		66 interacting genes: ALDH2 ANXA1 ANXA7 AQP2 BAIAP2 BID BTBD2 CCDC106 CCL18 CDC42 CDK5RAP2 CELF3 CLN8 COX17 CRADD CREB1 CREB3 CSTF2 DYNLL1 FAS FCGR2B FXR1 GADD45A GSK3B HMGB1 HNRNPH3 HNRNPUL1 HSPE1 HYLS1 KLHL20 LMNA LSM2 MAPK8IP2 MPHOSPH6 MRPL38 MRPS12 MTNR1B NAT9 NDUFA4L2 NR1H2 NSF PAFAH1B3 PCDHA4 PEX2 PFN1 PHYHIP POLE2 POLR2C POLR3F PPP1R8 PQBP1 RAB27A RPS6KA6 S100A8 SAT1 SEPHS1 SERPINB9 SNRPB SNRPG SULT1E1 TFG TK1 TSC22D1 TTR ZFP64 ZNF24	6 interacting genes: APP ELOC ERG28 PEX10 PLEKHF2 TLE1
Entrez ID		11161	5828
HPRD ID		05201	01367
Ensembl ID		ENSG00000133935	ENSG00000164751
Uniprot IDs		Q6FII3 Q86TW5 Q9UKR5	P28328
PDB IDs
Enriched GO Terms of Interacting Partners?
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