CCDC102B and ABI2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CCDC102B	ABI2
Description		coiled-coil domain containing 102B	abl interactor 2
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Cytoplasm Cytosol Cytoskeleton Adherens Junction Lamellipodium SCAR Complex Filopodium Tip Dendritic Spine
	Molecular Function	Protein Binding	DNA Binding Protein Binding Cytoskeletal Adaptor Activity SH3 Domain Binding Kinase Binding Ubiquitin Protein Ligase Binding Rac GTPase Binding Proline-rich Region Binding
	Biological Process		Cytoskeleton Organization Actin Polymerization Or Depolymerization Viral Process Cell Migration Rac Protein Signal Transduction Peptidyl-tyrosine Phosphorylation Regulation Of Dendritic Spine Morphogenesis Lens Fiber Cell Morphogenesis Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways			Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation VEGFA-VEGFR2 Pathway RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Caudate activity during reward ( 28927378) Liver enzyme levels (alanine transaminase) ( 24124411) Myopic maculopathy ( 29725004) Pursuit maintenance gain ( 29064472) Pursuit maintenance gain in psychotic disorders ( 29064472) Rostral anterior cingulate cortex volume ( 31530798)	Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Butyrylcholinesterase levels ( 21862451) Diverticular disease ( 30177863) Subclinical atherosclerosis traits (other) ( 17903303) Trunk fat mass ( 28552196) Urinary albumin-to-creatinine ratio ( 31511532)
Interacting Genes		51 interacting genes: ABI2 AK8 ARL4A ARL4D BYSL CCDC120 CCDC33 CCHCR1 CDK18 CEP19 CEP57L1 EHHADH ENKD1 EXOC5 FAM161A FBF1 FNDC11 GEM HMG20B KIFC3 LENG1 LMO4 LNX1 MAB21L2 MAGOHB MARK1 MCM7 MOS NIF3L1 NTAQ1 NXT2 PNMA5 POP5 PPP1R18 PSMA1 RCOR3 RSPH14 RTL8A RTL8B SDCBP SFN SGF29 SLIRP SPG21 SYCE1 TPM3 TRIM27 TRIM54 ZNF20 ZNF250 ZNF572	61 interacting genes: ABL1 ADAM19 ARHGAP32 ARMC7 BLOC1S6 CCDC102B CCHCR1 CDK6 CRX DTNB EFS EGLN3 EIF3H ENAH GCC1 HGS HNRNPK HOMER3 IFT20 IHO1 KHDRBS1 KIAA1217 KIFC3 KRT13 KRT15 KRT19 KRT20 KRT31 KRT33B LMO2 MCM7 MRFAP1L1 MRPL44 NCK1 NCK2 NUP62 PCM1 PIN1 PPIF PRAM1 PRKAA1 PRKAA2 PRR16 SDCBP SH3KBP1 SMARCB1 SNAP23 STAM2 TFIP11 TLE5 TRAF3IP1 TRIM32 TRIP6 VARS2 VASP VCL VPS37C WASF2 WASHC3 WIPF1 ZNF688
Entrez ID		79839	10152
HPRD ID		08038	07338
Ensembl ID		ENSG00000150636	ENSG00000138443
Uniprot IDs		Q68D86	A0A0C4DG21 B7Z836 E9PEZ7 F8WAL6 Q9NYB9
PDB IDs			2ED0 3P8C 4N78
Enriched GO Terms of Interacting Partners?
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