LAPTM5 and DCUN1D1

Number of citations of the paper that reports this interaction (PubMedID 15231748)
85

Data Source:
HPRD (two hybrid)

		LAPTM5	DCUN1D1
Description		lysosomal protein transmembrane 5	defective in cullin neddylation 1 domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Integral Component Of Plasma Membrane Membrane	Ubiquitin Ligase Complex Nucleoplasm Cytosol
	Molecular Function	Protein Binding	Protein Binding Ubiquitin Conjugating Enzyme Binding Ubiquitin-like Protein Binding Cullin Family Protein Binding
	Biological Process	Cellular Response To Leukemia Inhibitory Factor	Post-translational Protein Modification Protein Neddylation Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Protein Neddylation
Pathways			Neddylation
Drugs
Diseases
GWAS		Loneliness ( 27629369) Loneliness (linear analysis) ( 27629369)	Parkinson's disease ( 27182965 28011712) Subjective response to lithium treatment ( 26503763)
Interacting Genes		25 interacting genes: ANKRD13A DCUN1D1 DISP1 EPN1 EPN2 EPN3 EPS15 HERC1 HEY1 HEYL HUWE1 ITCH KRT7 LDLRAD1 NEDD4 NEDD4L RNF168 SMURF2 TNFAIP3 TOM1L2 UBA52 UBAC1 UBC USP13 WWP1	25 interacting genes: ARIH1 ARIH2 ARRDC3 AURKB CALM1 CAND1 CUL5 DAZAP2 DVL2 LAPTM5 LZTS2 MAP3K1 NEDD4 RHOA RNF11 SMAD2 TLE5 TP53BP2 TRIM39 TRIM54 UBC UBE2D3 UBE2F UBE2M VPS37B
Entrez ID		7805	54165
HPRD ID		03280	12067
Ensembl ID		ENSG00000162511	ENSG00000043093
Uniprot IDs		Q13571 Q5TBB8	B4DM76 C9JVE2 Q96GG9
PDB IDs			3TDU 3TDZ 4P5O 5UFI 5V83 5V86 5V88 6B5Q 6BG3 6BG5 6P5V 6P5W
Enriched GO Terms of Interacting Partners?
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