DCUN1D1 and ARRDC3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		DCUN1D1	ARRDC3
Description		defective in cullin neddylation 1 domain containing 1	arrestin domain containing 3
Image
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleoplasm Cytosol	Lysosome Endosome Early Endosome Plasma Membrane
	Molecular Function	Protein Binding Ubiquitin Conjugating Enzyme Binding Ubiquitin-like Protein Binding Cullin Family Protein Binding	Protein Binding Beta-3 Adrenergic Receptor Binding
	Biological Process	Post-translational Protein Modification Protein Neddylation Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Protein Neddylation	Temperature Homeostasis Negative Regulation Of Heat Generation Skin Development Positive Regulation Of Ubiquitin-protein Transferase Activity Fat Pad Development Negative Regulation Of Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Negative Regulation Of Locomotion Involved In Locomotory Behavior Negative Regulation Of Cold-induced Thermogenesis
Pathways		Neddylation
Drugs
Diseases
GWAS		Parkinson's disease ( 27182965 28011712) Subjective response to lithium treatment ( 26503763)	Breast cancer ( 29059683 25038754) Breast cancer (prognosis) ( 23319801) Breast cancer (survival) ( 25526632) Subcutaneous adipose tissue ( 22589738)
Interacting Genes		25 interacting genes: ARIH1 ARIH2 ARRDC3 AURKB CALM1 CAND1 CUL5 DAZAP2 DVL2 LAPTM5 LZTS2 MAP3K1 NEDD4 RHOA RNF11 SMAD2 TLE5 TP53BP2 TRIM39 TRIM54 UBC UBE2D3 UBE2F UBE2M VPS37B	14 interacting genes: ADRB2 BAG3 DCUN1D1 F2R HPGDS ITCH MAGI2 MORF4L1 OTUB2 PDCD6IP STAM2 TNFAIP3 TRIM42 UBE2E2
Entrez ID		54165	57561
HPRD ID		12067	09810
Ensembl ID		ENSG00000043093	ENSG00000113369
Uniprot IDs		B4DM76 C9JVE2 Q96GG9	Q96B67
PDB IDs		3TDU 3TDZ 4P5O 5UFI 5V83 5V86 5V88 6B5Q 6BG3 6BG5 6P5V 6P5W	4N7H 4R7V 4R7X
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?