YES1 and SSBP3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		YES1	SSBP3
Description		YES proto-oncogene 1, Src family tyrosine kinase	single stranded DNA binding protein 3
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Microtubule Organizing Center Cytosol Actin Filament Plasma Membrane Focal Adhesion Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Extracellular Exosome Glutamatergic Synapse Postsynaptic Specialization, Intracellular Component	Nucleus Transcription Factor Complex
	Molecular Function	Phosphotyrosine Residue Binding Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Signaling Receptor Binding Epidermal Growth Factor Receptor Binding Protein Binding ATP Binding Enzyme Binding Ion Channel Binding	Single-stranded DNA Binding Protein Binding
	Biological Process	Cellular Protein Modification Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Glucose Transmembrane Transport Cell Differentiation T Cell Costimulation Cellular Response To Platelet-derived Growth Factor Stimulus Peptidyl-tyrosine Autophosphorylation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Regulation Of Cell Proliferation Regulation Of Vascular Permeability Positive Regulation Of Transcription By RNA Polymerase II Ephrin Receptor Signaling Pathway Positive Regulation Of Peptidyl-tyrosine Phosphorylation Leukocyte Migration Cellular Response To Retinoic Acid Cellular Response To Transforming Growth Factor Beta Stimulus	Hematopoietic Progenitor Cell Differentiation Positive Regulation Of Cell Proliferation Prechordal Plate Formation Midbrain-hindbrain Boundary Initiation Positive Regulation Of Transcription By RNA Polymerase II Mesendoderm Development Head Development Head Morphogenesis Protein-containing Complex Assembly Positive Regulation Of Anterior Head Development
Pathways		Signaling by ERBB2 Signaling by SCF-KIT Signaling by SCF-KIT Regulation of KIT signaling FCGR activation PECAM1 interactions EPH-Ephrin signaling CD28 co-stimulation CTLA4 inhibitory signaling EPHB-mediated forward signaling EPHB-mediated forward signaling EPHA-mediated growth cone collapse EPHA-mediated growth cone collapse EPH-ephrin mediated repulsion of cells RUNX2 regulates osteoblast differentiation Regulation of signaling by CBL Regulation of signaling by CBL FCGR3A-mediated IL10 synthesis FCGR3A-mediated phagocytosis
Drugs		Dasatinib
Diseases
GWAS		Diastolic blood pressure ( 29403010 30487518) Hypertension ( 30487518) Mean arterial pressure ( 29403010 30487518) PR interval in Tripanosoma cruzi seropositivity ( 24324551) Pulmonary function in asthmatics ( 23541324) Pursuit maintenance gain ( 29064472) Systolic blood pressure ( 30224653 29403010 30487518 30578418)	Blood urea nitrogen levels ( 31152163 29403010) Body mass index ( 25673413) Food allergy ( 25710614) Menarche (age at onset) ( 27182965) P wave duration ( 28794112) Platelet distribution width ( 27863252) Serum bilirubin levels in metabolic syndrome ( 30621171) T wave morphology restitution during recovery from exercise ( 31607149) T wave morphology restitution during recovery from exercise (MTAG) ( 31607149)
Interacting Genes		54 interacting genes: ADAM12 ADAM15 BECN1 C1orf94 CBL CD2AP CD36 CD46 CDH1 CDKN1B CSF1R DLG4 DOK1 DVL2 EPHB2 FASLG FGFR1 FLT1 FUNDC1 FXR2 GP6 ITGB4 JAK2 KDR KHDRBS1 KIT MST1R NEDD4 NIF3L1 NPHS1 OGT PAK2 PDCD6IP PDGFRB PECAM1 PTEN PTK2 PTPRE RASA1 RPL10 SKAP2 SLC9A3R1 SOCS3 SPRR2A SSBP3 THAP1 TNK2 TP53BP2 TRAF2 TRAF6 TRPV4 TYRO3 ZBTB8A ZNF512B	17 interacting genes: ANKEF1 APP ARNT2 CLK1 EWSR1 HCLS1 IL36RN LDB1 LDB2 NXT2 PIN1 RFC1 SIVA1 SUPT5H TBC1D23 YES1 ZNF226
Entrez ID		7525	23648
HPRD ID		01285	09578
Ensembl ID		ENSG00000176105	ENSG00000157216
Uniprot IDs		P07947	Q9BWW4 Q9NW25
PDB IDs		2HDA
Enriched GO Terms of Interacting Partners?
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