SSBP3 and SUPT5H

Number of citations of the paper that reports this interaction (PubMedID 20211142)
329

Data Source:
BioGRID (two hybrid)

		SSBP3	SUPT5H
Description		single stranded DNA binding protein 3	SPT5 homolog, DSIF elongation factor subunit
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Transcription Factor Complex	Nucleus Nucleoplasm DSIF Complex
	Molecular Function	Single-stranded DNA Binding Protein Binding	Chromatin Binding RNA Binding MRNA Binding Protein Binding Enzyme Binding Protein Heterodimerization Activity
	Biological Process	Hematopoietic Progenitor Cell Differentiation Positive Regulation Of Cell Proliferation Prechordal Plate Formation Midbrain-hindbrain Boundary Initiation Positive Regulation Of Transcription By RNA Polymerase II Mesendoderm Development Head Development Head Morphogenesis Protein-containing Complex Assembly Positive Regulation Of Anterior Head Development	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter 7-methylguanosine MRNA Capping Positive Regulation Of Macroautophagy Negative Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Viral Transcription Negative Regulation Of MRNA Polyadenylation
Pathways			Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex RNA Pol II CTD phosphorylation and interaction with CE during HIV infection Formation of HIV-1 elongation complex containing HIV-1 Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Abortive elongation of HIV-1 transcript in the absence of Tat Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA polymerase II transcribes snRNA genes mRNA Capping RNA Polymerase II Transcription Elongation RNA Pol II CTD phosphorylation and interaction with CE
Drugs
Diseases
GWAS		Blood urea nitrogen levels ( 31152163 29403010) Body mass index ( 25673413) Food allergy ( 25710614) Menarche (age at onset) ( 27182965) P wave duration ( 28794112) Platelet distribution width ( 27863252) Serum bilirubin levels in metabolic syndrome ( 30621171) T wave morphology restitution during recovery from exercise ( 31607149) T wave morphology restitution during recovery from exercise (MTAG) ( 31607149)
Interacting Genes		17 interacting genes: ANKEF1 APP ARNT2 CLK1 EWSR1 HCLS1 IL36RN LDB1 LDB2 NXT2 PIN1 RFC1 SIVA1 SUPT5H TBC1D23 YES1 ZNF226	44 interacting genes: C9orf78 CCNH CCNT1 CCNT2 CDK7 CDK9 CEP55 CSNK2A1 DBN1 DCAF6 FHL3 GOLGA2 GTF3C1 H2AX HSPB1 HTATSF1 IK IKBKG LMAN2 MAD1L1 MAML3 MNAT1 PCBD1 PHYHIP PIN1 PNO1 POLR2A PPIA PPP2R2D PRMT1 PRMT5 SAP30BP SIK1 SNX4 SSBP3 SUPT4H1 TERF1 TEX11 TLE5 XRCC5 ZBTB3 ZFYVE9 ZNF496 ZNF512B
Entrez ID		23648	6829
HPRD ID		09578	03655
Ensembl ID		ENSG00000157216	ENSG00000196235
Uniprot IDs		Q9BWW4 Q9NW25	O00267
PDB IDs			2DO3 2E6Z 2E70 3H7H 4L1U 5OHO 5OHQ 5OIK 5U98 6EQY 6ER0 6GMH 6GML
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?