SSBP3 and IL36RN

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SSBP3	IL36RN
Description		single stranded DNA binding protein 3	interleukin 36 receptor antagonist
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Transcription Factor Complex	Extracellular Region Extracellular Space
	Molecular Function	Single-stranded DNA Binding Protein Binding	Cytokine Activity Interleukin-1 Receptor Binding Interleukin-1 Receptor Antagonist Activity Protein Binding
	Biological Process	Hematopoietic Progenitor Cell Differentiation Positive Regulation Of Cell Proliferation Prechordal Plate Formation Midbrain-hindbrain Boundary Initiation Positive Regulation Of Transcription By RNA Polymerase II Mesendoderm Development Head Development Head Morphogenesis Protein-containing Complex Assembly Positive Regulation Of Anterior Head Development	Negative Regulation Of Cytokine-mediated Signaling Pathway Inflammatory Response To Antigenic Stimulus Inflammatory Response Cytokine-mediated Signaling Pathway Antifungal Humoral Response Negative Regulation Of Interleukin-17 Production Negative Regulation Of Interleukin-6 Production Innate Immune Response Cellular Response To Lipopolysaccharide Negative Regulation Of Interferon-gamma Secretion
Pathways			Interleukin-36 pathway
Drugs
Diseases
GWAS		Blood urea nitrogen levels ( 31152163 29403010) Body mass index ( 25673413) Food allergy ( 25710614) Menarche (age at onset) ( 27182965) P wave duration ( 28794112) Platelet distribution width ( 27863252) Serum bilirubin levels in metabolic syndrome ( 30621171) T wave morphology restitution during recovery from exercise ( 31607149) T wave morphology restitution during recovery from exercise (MTAG) ( 31607149)	Menstruation quality of life impact (dysmenorrhea) ( 29855537) Pain medicine use during menstruation ( 29855537) Stroke ( 26089329)
Interacting Genes		17 interacting genes: ANKEF1 APP ARNT2 CLK1 EWSR1 HCLS1 IL36RN LDB1 LDB2 NXT2 PIN1 RFC1 SIVA1 SUPT5H TBC1D23 YES1 ZNF226	7 interacting genes: MCM6 REL SKIL SSBP2 SSBP3 SSBP4 ZNF512B
Entrez ID		23648	26525
HPRD ID		09578	16112
Ensembl ID		ENSG00000157216	ENSG00000136695
Uniprot IDs		Q9BWW4 Q9NW25	A0A024R518 Q9UBH0
PDB IDs			4P0J 4P0K 4P0L
Enriched GO Terms of Interacting Partners?
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