SUMO1 and CANX

Number of citations of the paper that reports this interaction (PubMedID 25586181)
6

Data Source:
BioGRID (pull down)

		SUMO1	CANX
Description		small ubiquitin like modifier 1	calnexin
Image			No pdb structure
GO Annotations	Cellular Component	Heterochromatin Fibrillar Center XY Body Nucleus Nuclear Envelope Nuclear Pore Nucleoplasm Nucleolus Cytosol Plasma Membrane Voltage-gated Potassium Channel Complex Nuclear Body PML Body Nuclear Speck Dendrite SUMO Activating Enzyme Complex Nuclear Membrane Synapse Nuclear Stress Granule	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Smooth Endoplasmic Reticulum Rough Endoplasmic Reticulum Ribosome Membrane Axon Dendrite Cytoplasm Protein-containing Complex Melanosome Neuronal Cell Body Dendritic Spine Mitochondria-associated ER Membrane Endoplasmic Reticulum Quality Control Compartment Extracellular Exosome Integral Component Of Lumenal Side Of Endoplasmic Reticulum Membrane Glutamatergic Synapse Integral Component Of Postsynaptic Membrane Integral Component Of Presynaptic Active Zone Membrane
	Molecular Function	Transcription Corepressor Binding RNA Binding Protein Binding Protein C-terminus Binding Transcription Factor Binding Potassium Channel Regulator Activity Enzyme Binding Protein Binding, Bridging Protein Tag Ubiquitin Protein Ligase Binding Glucocorticoid Receptor Binding Small Protein Activating Enzyme Binding Ubiquitin-like Protein Ligase Binding	RNA Binding Calcium Ion Binding Protein Binding Carbohydrate Binding Apolipoprotein Binding Ionotropic Glutamate Receptor Binding Unfolded Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Repair Double-strand Break Repair Via Nonhomologous End Joining Viral Process Protein Sumoylation PML Body Organization Positive Regulation Of Protein Complex Assembly Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Localization Cellular Response To Heat Negative Regulation Of DNA Binding Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Action Potential Negative Regulation Of Transcription, DNA-templated Protein Stabilization Roof Of Mouth Development Regulation Of Interferon-gamma-mediated Signaling Pathway Cellular Response To Cadmium Ion Regulation Of Cardiac Muscle Cell Contraction Protein Localization To Nuclear Pore Positive Regulation Of Calcium-transporting ATPase Activity Negative Regulation Of Delayed Rectifier Potassium Channel Activity	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Protein Folding Aging Protein Secretion Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Endoplasmic Reticulum Unfolded Protein Response Protein Folding In Endoplasmic Reticulum Synaptic Vesicle Endocytosis Interleukin-27-mediated Signaling Pathway Interleukin-35-mediated Signaling Pathway Clathrin-dependent Endocytosis
Pathways		SUMO is conjugated to E1 (UBA2:SAE1) SUMO is transferred from E1 to E2 (UBE2I, UBC9) SUMO is proteolytically processed SUMOylation of DNA damage response and repair proteins SUMO E3 ligases SUMOylate target proteins SUMOylation of transcription factors SUMOylation of transcription factors SUMOylation of ubiquitinylation proteins SUMOylation of transcription cofactors SUMOylation of transcription cofactors SUMOylation of SUMOylation proteins SUMOylation of intracellular receptors SUMOylation of intracellular receptors SUMOylation of chromatin organization proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins SUMOylation of DNA methylation proteins SUMOylation of DNA methylation proteins SUMOylation of immune response proteins Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Nonhomologous End-Joining (NHEJ) Processing of DNA double-strand break ends Formation of Incision Complex in GG-NER G2/M DNA damage checkpoint Regulation of IFNG signaling Negative regulation of activity of TFAP2 (AP-2) family transcription factors Negative regulation of activity of TFAP2 (AP-2) family transcription factors Postmitotic nuclear pore complex (NPC) reformation	Assembly of Viral Components at the Budding Site MHC class II antigen presentation Interleukin-35 Signalling Calnexin/calreticulin cycle Interleukin-27 signaling Antigen Presentation: Folding, assembly and peptide loading of class I MHC Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs			Antihemophilic factor, human recombinant Tenecteplase Calcium Citrate Calcium Phosphate
Diseases
GWAS			Daytime sleep phenotypes ( 27126917) Myeloid white cell count ( 27863252) Resting heart rate ( 24680774) White blood cell count ( 27863252)
Interacting Genes		139 interacting genes: AR ATF2 ATXN1 ATXN3 ATXN7 AXIN1 BIRC3 BLM BRCA1 C11orf65 C18orf25 CANX CARD9 CASP2 CASP8 CDK6 CHAF1A CHD3 CREBBP DAXX DEUP1 DNM1 DNMT3B DTX2 EDARADD EGLN3 ETV6 FAF1 FAM118B FAS FASLG FBF1 FOS FOXM1 GMCL1 HDAC4 HDAC9 HGS HIF1A HIPK2 HIPK3 HNRNPC HNRNPK HSF1 HTT IKZF3 IRAK1 JUN MAPK1IP1L MDM2 MEF2A MITF MRTFA MSX1 MTOR MUL1 MYB NCOA1 NCOA2 NCOA3 NCOR2 NFE2L2 NFKBIA NIN NR3C1 NR3C2 PARK7 PAX6 PCNA PDGFC PHC1 PIAS1 PIAS2 PIAS3 PIAS4 PKM PLAGL1 PML PPM1J PRKN PSIP1 RAD51 RAD52 RAD54B RAD54L2 RANBP2 RANGAP1 RHOXF2 RNF111 RNF4 RPS3 SAE1 SALL1 SATB1 SENP1 SENP2 SENP6 SETX SLC2A1 SOX10 SOX2 SOX6 SP100 SP3 SPOP SREBF1 SREBF2 SUMO1P1 TDG TDP2 TFCP2 TNFRSF1A TOE1 TOP1 TOP2A TOP2B TOPORS TP53 TP73 TRAF4 TRIM24 TRPS1 TSC22D3 UBA2 UBE2I USP25 USPL1 WRN XPO1 ZBTB16 ZBTB26 ZBTB6 ZCCHC12 ZCCHC7 ZHX1 ZMYM2 ZMYM3 ZMYM5 ZNF451	44 interacting genes: ABCC2 APOB BCAP31 CD1D CD3D CD82 CFTR CSNK2A1 EBI3 EDEM1 F8 FAM107A FSHR GRIA1 GRIN1 HLA-A HTR3A IFNGR1 ITGA6 ITGB1 LCT LHCGR LPA LRP1 MBTPS1 MDM2 MTNR1A MTNR1B NDRG1 NUTF2 PDIA3 PLP1 PMP22 PRKCSH SERP1 SLC2A1 SLC4A1 SLC6A4 SMURF2 SUMO1 TF TG TRA TSHR
Entrez ID		7341	821
HPRD ID		03554	00252
Ensembl ID		ENSG00000116030	ENSG00000127022
Uniprot IDs		A0A024R3Z2 P63165	P27824
PDB IDs		1A5R 1TGZ 1WYW 1Y8R 1Z5S 2ASQ 2BF8 2G4D 2IO2 2IY0 2IY1 2KQS 2LAS 2MW5 2N1A 2N1V 2PE6 2UYZ 2VRR 3KYC 3KYD 3RZW 3UIP 4WJN 4WJO 4WJP 4WJQ 5AEK 5B7A 5ELJ 5GHD 6EOP 6EOT 6J4I 6K5T 6UYO 6UYP 6UYQ 6UYR 6UYS 6UYT 6UYU 6UYV 6UYX 6UYY 6UYZ
Enriched GO Terms of Interacting Partners?
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