C2 and MASP1

  • Number of citations of the paper that reports this interaction (PubMedID 10946292)
  • 48
  • Data Source:
  • HPRD (in vitro)

C2

MASP1

Description complement C2 mannan binding lectin serine peptidase 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Advanced age-related macular degeneration ( 26691988)
  • Age-related macular degeneration ( 20385819 20385826 23455636 21665990)
  • Age-related macular degeneration (choroidal neovascularisation) ( 22705344)
  • Age-related macular degeneration (geographic atrophy) ( 22705344)
  • Asthma ( 31619474)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Blood protein levels ( 30072576 29875488 28240269)
  • Circulating myeloperoxidase levels (serum) ( 23620142)
  • Coffee consumption ( 31046077)
  • Coronary artery disease ( 29212778 30104761)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Disease progression in age-related macular degeneration ( 29346644)
  • Endometriosis ( 28881265)
  • Estimated glomerular filtration rate ( 31451708)
  • Estimated glomerular filtration rate in diabetes ( 31451708)
  • Hepatocellular carcinoma ( 21105107)
  • Inflammatory bowel disease ( 28067908)
  • Itch intensity from mosquito bite adjusted by bite size ( 28199695)
  • Mosquito bite size ( 28199695)
  • Platelet aggregation ( 29185836)
  • Prostate cancer ( 23535732)
  • Sulfasalazine-induced agranulocytosis ( 28762467)
  • Systemic lupus erythematosus ( 24871463)
  • Ulcerative colitis ( 28067908)
Interacting Genes 6 interacting genes: C3 C4B C5 CREB3 MASP1 PSMA4 16 interacting genes: C2 C3 FCN2 GADD45A GSK3B H2AX MAPK6 MAPK8IP2 MAPT MBL2 NCK2 NUDT21 RPS6KA3 RPS6KA6 SERPING1 UFD1
Entrez ID 717 5648
HPRD ID 08939 02749
Ensembl ID ENSG00000166278 ENSG00000127241
Uniprot IDs A0A0G2JL69 B4DQI1 B4DV48 P06681 Q53HP3 Q5JP69 Q8N6L6 F8W876 P48740
PDB IDs 2I6Q 2I6S 2ODP 2ODQ 3ERB 3DEM 3GOV 4AQB 4DJZ 4IGD 4IW4 4KKD
Enriched GO Terms of Interacting Partners?
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