C2 and C3

  • Number of citations of the paper that reports this interaction (PubMedID 3546307)
  • 13
  • Data Source:
  • HPRD (in vitro)

C2

C3

Description complement C2 complement C3
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Advanced age-related macular degeneration ( 26691988)
  • Age-related macular degeneration ( 20385819 20385826 23455636 21665990)
  • Age-related macular degeneration (choroidal neovascularisation) ( 22705344)
  • Age-related macular degeneration (geographic atrophy) ( 22705344)
  • Asthma ( 31619474)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Blood protein levels ( 30072576 29875488 28240269)
  • Circulating myeloperoxidase levels (serum) ( 23620142)
  • Coffee consumption ( 31046077)
  • Coronary artery disease ( 29212778 30104761)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Disease progression in age-related macular degeneration ( 29346644)
  • Endometriosis ( 28881265)
  • Estimated glomerular filtration rate ( 31451708)
  • Estimated glomerular filtration rate in diabetes ( 31451708)
  • Hepatocellular carcinoma ( 21105107)
  • Inflammatory bowel disease ( 28067908)
  • Itch intensity from mosquito bite adjusted by bite size ( 28199695)
  • Mosquito bite size ( 28199695)
  • Platelet aggregation ( 29185836)
  • Prostate cancer ( 23535732)
  • Sulfasalazine-induced agranulocytosis ( 28762467)
  • Systemic lupus erythematosus ( 24871463)
  • Ulcerative colitis ( 28067908)
Interacting Genes 6 interacting genes: C3 C4B C5 CREB3 MASP1 PSMA4 30 interacting genes: ABL1 ATG16L1 C2 C3AR1 C5 C5AR2 CD46 CFB CFH CFHR3 CFHR4 CFHR5 CFI CFP CPN1 CR1 CR2 CTSG GC HMGB1 ITGAM ITGAX ITGB2 LAMA1 LRP1 MASP1 OLFM4 PAPPA TGM2 VSIG4
Entrez ID 717 718
HPRD ID 08939 00400
Ensembl ID ENSG00000166278 ENSG00000125730
Uniprot IDs A0A0G2JL69 B4DQI1 B4DV48 P06681 Q53HP3 Q5JP69 Q8N6L6 B4DR57 P01024 V9HWA9
PDB IDs 2I6Q 2I6S 2ODP 2ODQ 3ERB 1C3D 1GHQ 1W2S 2A73 2A74 2GOX 2I07 2ICE 2ICF 2NOJ 2QKI 2WII 2WIN 2WY7 2WY8 2XQW 2XWB 2XWJ 3D5R 3D5S 3G6J 3L3O 3L5N 3NMS 3OED 3OHX 3OXU 3RJ3 3T4A 4HW5 4HWJ 4I6O 4M76 4ONT 4ZH1 5FO7 5FO8 5FO9 5FOA 5FOB 5NBQ 5O32 5O35 6EHG 6RUR 6RUV 6S0B
Enriched GO Terms of Interacting Partners?
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