TNNT2 and MORF4L2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TNNT2	MORF4L2
Description		troponin T2, cardiac type	mortality factor 4 like 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Troponin Complex Striated Muscle Thin Filament Sarcomere Cardiac Myofibril Cardiac Troponin Complex	Histone Acetyltransferase Complex Nucleoplasm Nucleolus Plasma Membrane NuA4 Histone Acetyltransferase Complex
	Molecular Function	Actin Binding Calcium Ion Binding Protein Binding Tropomyosin Binding Troponin C Binding Calcium-dependent ATPase Activity Troponin I Binding	Protein Binding
	Biological Process	Skeletal Muscle Contraction Muscle Contraction Regulation Of Muscle Contraction Regulation Of Heart Contraction Muscle Filament Sliding Negative Regulation Of ATPase Activity Positive Regulation Of ATPase Activity Sarcomere Organization Response To Calcium Ion Ventricular Cardiac Muscle Tissue Morphogenesis Cardiac Muscle Contraction	DNA Repair Chromatin Silencing Histone Acetylation Histone Deacetylation Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Striated Muscle Cell Differentiation
Pathways		Striated Muscle Contraction	HATs acetylate histones
Drugs
Diseases		Hypertrophic cardiomyopathy (HCM) Dilated cardiomyopathy (DCM)
GWAS		Cardiac Troponin-T levels ( 23247143) Height ( 28552196) Neurofibrillary tangles ( 25188341)
Interacting Genes		11 interacting genes: APP KDM1A MAP3K5 MORF4L2 MST1 NOTCH3 PRKCA TNNC1 TNNI1 TNNI3 TPM1	29 interacting genes: BEND7 CDR2 CEP55 DDIT4L FAM9B GLA GOLGA2 GRAMD2B HDAC1 IKZF1 KLHL3 L3MBTL3 LZTS2 MRFAP1 MRFAP1L1 MRGBP PHC2 PNMA2 RB1 SIN3A THAP1 TLE1 TLE5 TNIP1 TNNT2 ZBTB10 ZBTB14 ZBTB43 ZBTB7B
Entrez ID		7139	9643
HPRD ID		01844	02326
Ensembl ID		ENSG00000118194	ENSG00000123562
Uniprot IDs		A0A0A0MRJ5 P45379 Q15607	Q15014
PDB IDs		1J1D 1J1E 4Y99
Enriched GO Terms of Interacting Partners?
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