MORF4L2 and KLHL3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		MORF4L2	KLHL3
Description		mortality factor 4 like 2	kelch like family member 3
Image		No pdb structure
GO Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleoplasm Nucleolus Plasma Membrane NuA4 Histone Acetyltransferase Complex	Cytosol Cytoskeleton Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Binding	Actin Binding Structural Molecule Activity Protein Binding
	Biological Process	DNA Repair Chromatin Silencing Histone Acetylation Histone Deacetylation Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Striated Muscle Cell Differentiation	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Post-translational Protein Modification Ion Homeostasis Selective Autophagy Renal Sodium Ion Absorption Protein K48-linked Ubiquitination Distal Tubule Morphogenesis
Pathways		HATs acetylate histones	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Bronchopulmonary dysplasia ( 23897914) Heart failure ( 31919418) Severe malaria ( 29381699) Severe malaria (adjusted for sickle cell variant rs334) ( 29381699)
Interacting Genes		29 interacting genes: BEND7 CDR2 CEP55 DDIT4L FAM9B GLA GOLGA2 GRAMD2B HDAC1 IKZF1 KLHL3 L3MBTL3 LZTS2 MRFAP1 MRFAP1L1 MRGBP PHC2 PNMA2 RB1 SIN3A THAP1 TLE1 TLE5 TNIP1 TNNT2 ZBTB10 ZBTB14 ZBTB43 ZBTB7B	16 interacting genes: AKT1 CFAP206 CUL3 GNAI1 GNAO1 KEAP1 KLHL12 MORF4L2 OPRD1 PPP3CA PRKACA SYNCRIP SYT2 WNK1 WNK3 WNK4
Entrez ID		9643	26249
HPRD ID		02326	09011
Ensembl ID		ENSG00000123562	ENSG00000146021
Uniprot IDs		Q15014	Q9UH77
PDB IDs			4CH9 4HXI 5NKP
Enriched GO Terms of Interacting Partners?
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