TNNT2 and TNNI1

Number of citations of the paper that reports this interaction (PubMedID 15542288)
64

Data Source:
BioGRID (two hybrid)

		TNNT2	TNNI1
Description		troponin T2, cardiac type	troponin I1, slow skeletal type
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Troponin Complex Striated Muscle Thin Filament Sarcomere Cardiac Myofibril Cardiac Troponin Complex	Cytosol Troponin Complex
	Molecular Function	Actin Binding Calcium Ion Binding Protein Binding Tropomyosin Binding Troponin C Binding Calcium-dependent ATPase Activity Troponin I Binding	Actin Binding Protein Binding Metal Ion Binding
	Biological Process	Skeletal Muscle Contraction Muscle Contraction Regulation Of Muscle Contraction Regulation Of Heart Contraction Muscle Filament Sliding Negative Regulation Of ATPase Activity Positive Regulation Of ATPase Activity Sarcomere Organization Response To Calcium Ion Ventricular Cardiac Muscle Tissue Morphogenesis Cardiac Muscle Contraction	Skeletal Muscle Contraction Muscle Contraction Regulation Of Striated Muscle Contraction Transition Between Fast And Slow Fiber Muscle Filament Sliding Ventricular Cardiac Muscle Tissue Morphogenesis Cardiac Muscle Contraction
Pathways		Striated Muscle Contraction	Striated Muscle Contraction
Drugs
Diseases		Hypertrophic cardiomyopathy (HCM) Dilated cardiomyopathy (DCM)
GWAS		Cardiac Troponin-T levels ( 23247143) Height ( 28552196) Neurofibrillary tangles ( 25188341)
Interacting Genes		11 interacting genes: APP KDM1A MAP3K5 MORF4L2 MST1 NOTCH3 PRKCA TNNC1 TNNI1 TNNI3 TPM1	10 interacting genes: ACTA1 CCDC85B MDFI PKD2L1 PNMA1 TNNC1 TNNT1 TNNT2 TRIM55 TRIM63
Entrez ID		7139	7135
HPRD ID		01844	01842
Ensembl ID		ENSG00000118194	ENSG00000159173
Uniprot IDs		A0A0A0MRJ5 P45379 Q15607	P19237
PDB IDs		1J1D 1J1E 4Y99
Enriched GO Terms of Interacting Partners?
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