TNNI1 and TNNT2

Number of citations of the paper that reports this interaction (PubMedID 15542288)
64

Data Source:
BioGRID (two hybrid)

		TNNI1	TNNT2
Description		troponin I1, slow skeletal type	troponin T2, cardiac type
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Troponin Complex	Cytosol Troponin Complex Striated Muscle Thin Filament Sarcomere Cardiac Myofibril Cardiac Troponin Complex
	Molecular Function	Actin Binding Protein Binding Metal Ion Binding	Actin Binding Calcium Ion Binding Protein Binding Tropomyosin Binding Troponin C Binding Calcium-dependent ATPase Activity Troponin I Binding
	Biological Process	Skeletal Muscle Contraction Muscle Contraction Regulation Of Striated Muscle Contraction Transition Between Fast And Slow Fiber Muscle Filament Sliding Ventricular Cardiac Muscle Tissue Morphogenesis Cardiac Muscle Contraction	Skeletal Muscle Contraction Muscle Contraction Regulation Of Muscle Contraction Regulation Of Heart Contraction Muscle Filament Sliding Negative Regulation Of ATPase Activity Positive Regulation Of ATPase Activity Sarcomere Organization Response To Calcium Ion Ventricular Cardiac Muscle Tissue Morphogenesis Cardiac Muscle Contraction
Pathways		Striated Muscle Contraction	Striated Muscle Contraction
Drugs
Diseases			Hypertrophic cardiomyopathy (HCM) Dilated cardiomyopathy (DCM)
GWAS			Cardiac Troponin-T levels ( 23247143) Height ( 28552196) Neurofibrillary tangles ( 25188341)
Interacting Genes		10 interacting genes: ACTA1 CCDC85B MDFI PKD2L1 PNMA1 TNNC1 TNNT1 TNNT2 TRIM55 TRIM63	11 interacting genes: APP KDM1A MAP3K5 MORF4L2 MST1 NOTCH3 PRKCA TNNC1 TNNI1 TNNI3 TPM1
Entrez ID		7135	7139
HPRD ID		01842	01844
Ensembl ID		ENSG00000159173	ENSG00000118194
Uniprot IDs		P19237	A0A0A0MRJ5 P45379 Q15607
PDB IDs			1J1D 1J1E 4Y99
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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