ARMC8 and CTNNA1

Number of citations of the paper that reports this interaction (PubMedID 18215130)
15

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		ARMC8	CTNNA1
Description		armadillo repeat containing 8	catenin alpha 1
Image		No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Extracellular Region Nucleus Cytoplasm GID Complex Specific Granule Lumen Tertiary Granule Lumen	Acrosomal Vesicle Cytosol Plasma Membrane Cell-cell Junction Zonula Adherens Focal Adhesion Intercalated Disc Actin Cytoskeleton Catenin Complex Flotillin Complex Lamellipodium Cell Junction Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	RNA Binding Structural Molecule Activity Protein Binding Beta-catenin Binding Vinculin Binding Identical Protein Binding Gamma-catenin Binding Cadherin Binding Actin Filament Binding
	Biological Process	Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Neutrophil Degranulation	Ovarian Follicle Development Cell Adhesion Establishment Or Maintenance Of Cell Polarity Negative Regulation Of Neuroblast Proliferation Aging Male Gonad Development Gap Junction Assembly Axon Regeneration Adherens Junction Organization Cellular Protein Localization Odontogenesis Of Dentin-containing Tooth Apical Junction Assembly Response To Estrogen Positive Regulation Of Smoothened Signaling Pathway Positive Regulation Of Muscle Cell Differentiation Cellular Response To Indole-3-methanol Epithelial Cell-cell Adhesion Negative Regulation Of Cell Motility Negative Regulation Of Integrin-mediated Signaling Pathway Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways		Neutrophil degranulation	Adherens junctions interactions VEGFR2 mediated vascular permeability Myogenesis Myogenesis RHO GTPases activate IQGAPs
Drugs
Diseases
GWAS			General risk tolerance (MTAG) ( 30643258) Schizophrenia ( 25056061)
Interacting Genes		4 interacting genes: CTNNA1 MAEA TCF12 TNNT1	31 interacting genes: ACTN1 AFDN AJUBA APC APP ARMC8 CA9 CDH1 CDH15 CDH2 CDH3 CDH5 CSNK2A1 CTBP1 CTNNB1 DLG1 JUP LRATD2 MTNR1A MTNR1B OBI1 PKD1 PSEN1 SASH1 SPTAN1 SPTBN1 TJP1 TJP2 UBE2I VCL ZGPAT
Entrez ID		25852	1495
HPRD ID		09992	00285
Ensembl ID		ENSG00000114098	ENSG00000044115
Uniprot IDs		B7Z637 Q8IUR7	A0A384MDY0 B4DKT9 B4DU00 G3XAM7 P35221
PDB IDs			1H6G 4EHP 4IGG
Enriched GO Terms of Interacting Partners?
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