TLE2 and PRDM1

  • Number of citations of the paper that reports this interaction (PubMedID 9887105)
  • 81

TLE2

PRDM1

Description TLE family member 2, transcriptional corepressor PR/SET domain 1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs) ( 23648065)
  • Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel) ( 23648065)
  • Carboplatin disposition in epthelial ovarian cancer ( 29367611)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Crohn's disease ( 21102463)
  • Diastolic blood pressure ( 30224653)
  • Monobrow ( 27182965)
  • Multiple myeloma ( 27363682)
  • Response to (pegylated) interferon in HBeAG-positive hepatitis B ( 30715261)
  • Sjögren's syndrome ( 24097067)
  • Systemic lupus erythematosus ( 27399966 23273568 26502338 28714469 19838193 19838195)
  • Systemic sclerosis ( 28314753)
Interacting Genes 16 interacting genes: BARHL1 EMX2 FOXA3 H3-3A HES1 HMGB1 LEF1 MSX1 MSX2 PAX9 PRDM1 RUNX1 TLE1 TLX3 UTY VENTX 11 interacting genes: ATXN1 EXOSC3 H1-1 H3C15 IKZF3 IRF4 KDM1A PIAS1 TLE1 TLE2 TLE5
Entrez ID 7089 639
HPRD ID 03025 04572
Ensembl ID ENSG00000065717 ENSG00000057657
Uniprot IDs K7EMK7 Q04725 A0A3B3IU23 B4DW27 O75626 Q5T4E8
PDB IDs 3DAL
Enriched GO Terms of Interacting Partners?
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