STAC and NCKIPSD

Number of citations of the paper that reports this interaction (PubMedID 18654987)
16

Data Source:
BioGRID (two hybrid)

		STAC	NCKIPSD
Description		SH3 and cysteine rich domain	NCK interacting protein with SH3 domain
Image
GO Annotations	Cellular Component	Cytosol T-tubule Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane	Cytosol Intermediate Filament COP9 Signalosome
	Molecular Function	Protein Binding Ion Channel Binding Metal Ion Binding	Protein Binding Cytoskeletal Protein Binding SH3 Domain Binding
	Biological Process	Skeletal Muscle Contraction Signal Transduction Cellular Response To Heat Intracellular Signal Transduction Positive Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Cation Channel Activity	Cytoskeleton Organization Positive Regulation Of Neuron Projection Development Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Pathways			Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Age-related cognitive decline (global cognition) (slope of z-scores) ( 30954325) Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Asthma ( 29273806) Brooding (response to stress) ( 30886212) Celiac disease ( 23936387) Erectile dysfunction in type 1 diabetes ( 22704111) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Kidney disease (end stage renal disease vs non-end stage renal disease) in type 1 diabetes ( 31537649) Metabolite levels ( 23823483) Smoking behaviour (maximum cigarettes in a 24 hour period) ( 29532581)	Anorexia nervosa ( 31308545) Blood protein levels ( 28240269) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Intelligence (MTAG) ( 29326435) Parkinson's disease ( 28892059) Ulcerative colitis ( 28067908)
Interacting Genes		13 interacting genes: APP FBXO25 KANK2 KIAA1958 LIMD1 LMNA LRRK2 LZTS2 NCKIPSD NEDD4L PJA1 TRIP6 TRMO	20 interacting genes: ARHGEF7 BAIAP2 DIAPH2 DIAPH3 DLG4 DMRTB1 FASLG GRB2 HSPB1 ITGB1 KHDRBS1 MAPK3 NCK1 NCK2 PSMD9 SORBS3 STAC WAS WASL YWHAG
Entrez ID		6769	51517
HPRD ID		11890	09450
Ensembl ID		ENSG00000144681	ENSG00000213672
Uniprot IDs		B4DR96 B4DZ13 E9PEA7 Q8WUK8 Q99469	Q9NZQ3
PDB IDs		2DL4 6B25	6DEC 6DED 6DEE
Enriched GO Terms of Interacting Partners?
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