NCKIPSD and STAC

Number of citations of the paper that reports this interaction (PubMedID 18654987)
16

Data Source:
BioGRID (two hybrid)

		NCKIPSD	STAC
Description		NCK interacting protein with SH3 domain	SH3 and cysteine rich domain
Image
GO Annotations	Cellular Component	Cytosol Intermediate Filament COP9 Signalosome	Cytosol T-tubule Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
	Molecular Function	Protein Binding Cytoskeletal Protein Binding SH3 Domain Binding	Protein Binding Ion Channel Binding Metal Ion Binding
	Biological Process	Cytoskeleton Organization Positive Regulation Of Neuron Projection Development Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis	Skeletal Muscle Contraction Signal Transduction Cellular Response To Heat Intracellular Signal Transduction Positive Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Cation Channel Activity
Pathways		Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Anorexia nervosa ( 31308545) Blood protein levels ( 28240269) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Intelligence (MTAG) ( 29326435) Parkinson's disease ( 28892059) Ulcerative colitis ( 28067908)	Age-related cognitive decline (global cognition) (slope of z-scores) ( 30954325) Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Asthma ( 29273806) Brooding (response to stress) ( 30886212) Celiac disease ( 23936387) Erectile dysfunction in type 1 diabetes ( 22704111) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Kidney disease (end stage renal disease vs non-end stage renal disease) in type 1 diabetes ( 31537649) Metabolite levels ( 23823483) Smoking behaviour (maximum cigarettes in a 24 hour period) ( 29532581)
Interacting Genes		20 interacting genes: ARHGEF7 BAIAP2 DIAPH2 DIAPH3 DLG4 DMRTB1 FASLG GRB2 HSPB1 ITGB1 KHDRBS1 MAPK3 NCK1 NCK2 PSMD9 SORBS3 STAC WAS WASL YWHAG	13 interacting genes: APP FBXO25 KANK2 KIAA1958 LIMD1 LMNA LRRK2 LZTS2 NCKIPSD NEDD4L PJA1 TRIP6 TRMO
Entrez ID		51517	6769
HPRD ID		09450	11890
Ensembl ID		ENSG00000213672	ENSG00000144681
Uniprot IDs		Q9NZQ3	B4DR96 B4DZ13 E9PEA7 Q8WUK8 Q99469
PDB IDs		6DEC 6DED 6DEE	2DL4 6B25
Enriched GO Terms of Interacting Partners?
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