STAC and KANK2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		STAC	KANK2
Description		SH3 and cysteine rich domain	KN motif and ankyrin repeat domains 2
Image
GO Annotations	Cellular Component	Cytosol T-tubule Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane	Cytoplasm Mitochondrion
	Molecular Function	Protein Binding Ion Channel Binding Metal Ion Binding	Protein Binding
	Biological Process	Skeletal Muscle Contraction Signal Transduction Cellular Response To Heat Intracellular Signal Transduction Positive Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Cation Channel Activity	Negative Regulation Of Transcription By RNA Polymerase II Apoptotic Process Negative Regulation Of Cell Proliferation Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Regulation Of Rho Protein Signal Transduction Negative Regulation Of Programmed Cell Death Negative Regulation Of Vitamin D Receptor Signaling Pathway Kidney Epithelium Development Glomerular Visceral Epithelial Cell Migration Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
Drugs
Diseases
GWAS		Age-related cognitive decline (global cognition) (slope of z-scores) ( 30954325) Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Asthma ( 29273806) Brooding (response to stress) ( 30886212) Celiac disease ( 23936387) Erectile dysfunction in type 1 diabetes ( 22704111) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Kidney disease (end stage renal disease vs non-end stage renal disease) in type 1 diabetes ( 31537649) Metabolite levels ( 23823483) Smoking behaviour (maximum cigarettes in a 24 hour period) ( 29532581)	Cholesterol, total ( 26780889) Coronary artery disease ( 29212778) HDL cholesterol ( 23505323) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Immature fraction of reticulocytes ( 27863252) Intraocular pressure ( 31959993) Red cell distribution width ( 27863252 28957414) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252)
Interacting Genes		13 interacting genes: APP FBXO25 KANK2 KIAA1958 LIMD1 LMNA LRRK2 LZTS2 NCKIPSD NEDD4L PJA1 TRIP6 TRMO	23 interacting genes: ABI3 CCDC33 CEP70 CSNK2A1 DYNLL1 EIF4E FHL2 GOLGA2 GPSM1 IHO1 LMO1 LMO2 LMO4 MAGEB4 MOB1A NCOA1 NOS3 PSEN1 SRPK2 STAC TLE5 TXLNA VPS52
Entrez ID		6769	25959
HPRD ID		11890	12463
Ensembl ID		ENSG00000144681	ENSG00000197256
Uniprot IDs		B4DR96 B4DZ13 E9PEA7 Q8WUK8 Q99469	Q63ZY3
PDB IDs		2DL4 6B25	4HBD 5YBV
Enriched GO Terms of Interacting Partners?
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