SREBF2 and EGR1

  • Number of citations of the paper that reports this interaction (PubMedID 20936779)
  • 85
  • Data Source:
  • BioGRID (two hybrid)

SREBF2

EGR1

Description sterol regulatory element binding transcription factor 2 early growth response 1
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Amyotrophic lateral sclerosis (C9orf72 mutation interaction) ( 22959728)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321)
  • Schizophrenia ( 28991256 25056061)
Interacting Genes 50 interacting genes: ABLIM1 ABLIM2 ARHGEF1 ARRB1 ATF7IP ATXN1 AURKA CASP3 CASP8AP2 COPS5 CREB1 CREBBP EGR1 EP300 FHL3 GOLGB1 HNF4A HSPA5 INSIG1 INSIG2 ITGB4 KLF13 KPNB1 LINC00839 LZTR1 MAPK1 MAPK3 MRPS6 MTNR1B NAE1 NFYA NFYC OS9 PIAS1 PIAS2 PIAS3 PSMD4 RAB11B SCAP SLC4A4 SMAD3 SP1 SPTBN1 SREBF1 SUMO1 TTC1 UBE2I ZDHHC17 ZMYM2 ZYX 23 interacting genes: CDKN2A CEBPB CRBN CREBBP CSNK2A1 DNMT3L EP300 ERBB3 IL1B JUN MTDH NAB1 NAB2 NFATC1 NFATC2 PITX1 PSMA3 RELA SP1 SRA1 SREBF2 TP53 WT1
Entrez ID 6721 1958
HPRD ID 02726 00549
Ensembl ID ENSG00000198911 ENSG00000120738
Uniprot IDs A0A024R1Q0 Q12772 P18146 Q546S1
PDB IDs 1UKL 4R2A 4R2C 4R2D 4X9J 5N14
Enriched GO Terms of Interacting Partners?
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