EGR1 and ERBB3

  • Number of citations of the paper that reports this interaction (PubMedID 12840049)
  • 25
  • Data Source:
  • BioGRID (protein complementation assay)

EGR1

ERBB3

Description early growth response 1 erb-b2 receptor tyrosine kinase 3
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Amyotrophic lateral sclerosis (C9orf72 mutation interaction) ( 22959728)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321)
  • Schizophrenia ( 28991256 25056061)
Interacting Genes 23 interacting genes: CDKN2A CEBPB CRBN CREBBP CSNK2A1 DNMT3L EP300 ERBB3 IL1B JUN MTDH NAB1 NAB2 NFATC1 NFATC2 PITX1 PSMA3 RELA SP1 SRA1 SREBF2 TP53 WT1 100 interacting genes: ABL1 ABL2 AGTR2 BCAR3 CD82 CDC25C CDK5 CHN2 CRK CRKL CSPG5 DAB1 DAPP1 DUPD1 DUSP14 DUSP18 DUSP19 DUSP21 EGF EGFR EGR1 ERBB2 ERBB4 EYA4 FER FGFR1 FLNA FLYWCH1 GRB2 GRB7 HCK HDAC6 IL6ST ILKAP ITK JAK2 JAK3 MTMR1 MTMR10 MTMR2 MTMR6 MTMR8 MTMR9 MUC1 MUC4 NCK1 NCK2 NEDD4 NRG1 NRG2 ODF2L PA2G4 PIK3R1 PIK3R2 PIK3R3 PLCG1 PPM1A PPM1B PPM1F PPM1K PPM1M PRKACA PTEN PTGES3 PTK2 PTK2B PTK6 PTPDC1 PTPN11 PTPN12 PTPN20 PTPN6 PTPN7 PTPRH PTPRR RASA1 RASA4 RGS4 RIN1 RNF41 RPN1 SH2B3 SH2D1A SHC1 SHC3 SOS1 SRC SRPK2 STYX SYK TNS2 TNS3 TNS4 TPTE TXK VAV1 VAV2 VAV3 ZAP70 ZNF207
Entrez ID 1958 2065
HPRD ID 00549 01820
Ensembl ID ENSG00000120738 ENSG00000065361
Uniprot IDs P18146 Q546S1 P21860
PDB IDs 4R2A 4R2C 4R2D 4X9J 5N14 1M6B 2L9U 3KEX 3LMG 3P11 4LEO 4P59 4RIW 4RIX 4RIY 5CUS 5O4O 5O7P 6OP9
Enriched GO Terms of Interacting Partners?
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