SPN and SIGLEC1

Number of citations of the paper that reports this interaction (PubMedID 11238599)
35

Data Source:
HPRD (in vivo)

		SPN	SIGLEC1
Description		sialophorin	sialic acid binding Ig like lectin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Uropod Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Microvillus Cell Surface Membrane PML Body Extracellular Exosome	Extracellular Region Plasma Membrane Integral Component Of Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Hsp70 Protein Binding Heat Shock Protein Binding	Carbohydrate Binding
	Biological Process	T-helper 1 Cell Lineage Commitment Chemotaxis Immune Response Cellular Defense Response Negative Regulation Of Cell Adhesion Establishment Or Maintenance Of Cell Polarity Signal Transduction Interferon-gamma Production Negative Regulation Of T Cell Proliferation Positive Regulation Of Tumor Necrosis Factor Biosynthetic Process Defense Response To Bacterium Leukocyte Migration Leukocyte Tethering Or Rolling Regulation Of T Cell Migration Positive Regulation Of T Cell Migration	Endocytosis Inflammatory Response Cell-matrix Adhesion Cell-cell Adhesion
Pathways		Cell surface interactions at the vascular wall Basigin interactions	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs			Beta-D-Glucose N-acetyl-alpha-neuraminic acid
Diseases
GWAS			Blood protein levels ( 29875488) IgM levels ( 28628107) Night sleep phenotypes ( 27126917) Visceral fat ( 30942860)
Interacting Genes		9 interacting genes: CTNNB1 DAXX EZR FYN ICAM1 LGALS1 LMNA MSN SIGLEC1	3 interacting genes: MUC1 SPN TNR
Entrez ID		6693	6614
HPRD ID		06770	02854
Ensembl ID		ENSG00000197471	ENSG00000088827
Uniprot IDs		A0A024R629 P16150	Q9BZZ2
PDB IDs
Enriched GO Terms of Interacting Partners?
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