SPN and MSN

Number of citations of the paper that reports this interaction (PubMedID 9616160)
34

Data Source:
HPRD (in vivo, in vitro)

		SPN	MSN
Description		sialophorin	moesin
Image		No pdb structure
GO Annotations	Cellular Component	Uropod Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Microvillus Cell Surface Membrane PML Body Extracellular Exosome	Uropod Extracellular Space Nucleus Cytoplasm Cytosol Cytoskeleton Plasma Membrane Microvillus Focal Adhesion Cell Surface Basolateral Plasma Membrane Apical Plasma Membrane Filopodium Pseudopodium Microvillus Membrane Vesicle Apical Part Of Cell Perinuclear Region Of Cytoplasm Extracellular Exosome Invadopodium Cell Periphery Blood Microparticle
	Molecular Function	Transmembrane Signaling Receptor Activity Hsp70 Protein Binding Heat Shock Protein Binding	Double-stranded RNA Binding Actin Binding Signaling Receptor Binding Structural Constituent Of Cytoskeleton Protein Binding Enzyme Binding Protein Kinase Binding Cell Adhesion Molecule Binding
	Biological Process	T-helper 1 Cell Lineage Commitment Chemotaxis Immune Response Cellular Defense Response Negative Regulation Of Cell Adhesion Establishment Or Maintenance Of Cell Polarity Signal Transduction Interferon-gamma Production Negative Regulation Of T Cell Proliferation Positive Regulation Of Tumor Necrosis Factor Biosynthetic Process Defense Response To Bacterium Leukocyte Migration Leukocyte Tethering Or Rolling Regulation Of T Cell Migration Positive Regulation Of T Cell Migration	Immunological Synapse Formation Cytoskeleton Organization Leukocyte Cell-cell Adhesion Regulation Of Cell Shape Regulation Of Cell Size Positive Regulation Of Gene Expression Viral Process Gland Morphogenesis Membrane To Membrane Docking Interleukin-12-mediated Signaling Pathway T Cell Proliferation Establishment Of Epithelial Cell Apical/basal Polarity Leukocyte Migration Establishment Of Endothelial Barrier T Cell Aggregation Cellular Response To Testosterone Stimulus Positive Regulation Of Podosome Assembly T Cell Migration Regulation Of Organelle Assembly Positive Regulation Of Protein Localization To Early Endosome Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Lymphocyte Migration Positive Regulation Of Early Endosome To Late Endosome Transport
Pathways		Cell surface interactions at the vascular wall Basigin interactions	Recycling pathway of L1 Recycling pathway of L1 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs
Diseases
GWAS			Male-pattern baldness ( 28196072)
Interacting Genes		9 interacting genes: CTNNB1 DAXX EZR FYN ICAM1 LGALS1 LMNA MSN SIGLEC1	28 interacting genes: BCAP31 CD44 CD46 CD93 CDK11B EZR ICAM1 ICAM2 ICAM3 L1CAM NCF1 NCF4 PLEC PPM1A PPM1B PRKAR2A PRKCQ ROCK1 SELL SELPLG SLC9A3R1 SMURF1 SPN TERF1 TRIM15 TSC1 VCAM1 VPS11
Entrez ID		6693	4478
HPRD ID		06770	02399
Ensembl ID		ENSG00000197471	ENSG00000147065
Uniprot IDs		A0A024R629 P16150	P26038 V9HWC0
PDB IDs			1E5W 1EF1 1SGH
Enriched GO Terms of Interacting Partners?
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