SIGLEC1 and SPN

Number of citations of the paper that reports this interaction (PubMedID 11238599)
35

Data Source:
HPRD (in vivo)

		SIGLEC1	SPN
Description		sialic acid binding Ig like lectin 1	sialophorin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Membrane	Uropod Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Microvillus Cell Surface Membrane PML Body Extracellular Exosome
	Molecular Function	Carbohydrate Binding	Transmembrane Signaling Receptor Activity Hsp70 Protein Binding Heat Shock Protein Binding
	Biological Process	Endocytosis Inflammatory Response Cell-matrix Adhesion Cell-cell Adhesion	T-helper 1 Cell Lineage Commitment Chemotaxis Immune Response Cellular Defense Response Negative Regulation Of Cell Adhesion Establishment Or Maintenance Of Cell Polarity Signal Transduction Interferon-gamma Production Negative Regulation Of T Cell Proliferation Positive Regulation Of Tumor Necrosis Factor Biosynthetic Process Defense Response To Bacterium Leukocyte Migration Leukocyte Tethering Or Rolling Regulation Of T Cell Migration Positive Regulation Of T Cell Migration
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Cell surface interactions at the vascular wall Basigin interactions
Drugs		Beta-D-Glucose N-acetyl-alpha-neuraminic acid
Diseases
GWAS		Blood protein levels ( 29875488) IgM levels ( 28628107) Night sleep phenotypes ( 27126917) Visceral fat ( 30942860)
Interacting Genes		3 interacting genes: MUC1 SPN TNR	9 interacting genes: CTNNB1 DAXX EZR FYN ICAM1 LGALS1 LMNA MSN SIGLEC1
Entrez ID		6614	6693
HPRD ID		02854	06770
Ensembl ID		ENSG00000088827	ENSG00000197471
Uniprot IDs		Q9BZZ2	A0A024R629 P16150
PDB IDs
Enriched GO Terms of Interacting Partners?
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