SPN and LGALS1

Number of citations of the paper that reports this interaction (PubMedID 10490978)
73

Data Source:
HPRD (in vitro, in vivo)

		SPN	LGALS1
Description		sialophorin	galectin 1
Image		No pdb structure
GO Annotations	Cellular Component	Uropod Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Microvillus Cell Surface Membrane PML Body Extracellular Exosome	Extracellular Region Extracellular Space Intracellular Cell Nucleus Cytoplasm Endoplasmic Reticulum Lumen Cytosol Cell Surface Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Transmembrane Signaling Receptor Activity Hsp70 Protein Binding Heat Shock Protein Binding	RNA Binding Protein Binding Carbohydrate Binding Lactose Binding Identical Protein Binding Laminin Binding
	Biological Process	T-helper 1 Cell Lineage Commitment Chemotaxis Immune Response Cellular Defense Response Negative Regulation Of Cell Adhesion Establishment Or Maintenance Of Cell Polarity Signal Transduction Interferon-gamma Production Negative Regulation Of T Cell Proliferation Positive Regulation Of Tumor Necrosis Factor Biosynthetic Process Defense Response To Bacterium Leukocyte Migration Leukocyte Tethering Or Rolling Regulation Of T Cell Migration Positive Regulation Of T Cell Migration	Plasma Cell Differentiation Apoptotic Process Negative Regulation Of Cell-substrate Adhesion Negative Regulation Of Neuron Projection Development T Cell Costimulation Positive Regulation Of Erythrocyte Aggregation Response To Isolation Stress Response To Drug Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Post-translational Protein Modification Cellular Protein Metabolic Process Myoblast Differentiation Positive Regulation Of Viral Entry Into Host Cell Response To Axon Injury Cellular Response To Glucose Stimulus Cellular Response To Organic Cyclic Compound Positive Regulation Of Dendritic Cell Differentiation
Pathways		Cell surface interactions at the vascular wall Basigin interactions	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs			Beta-Mercaptoethanol Thiodigalactoside 1,4-Dithiothreitol Artenimol
Diseases
GWAS			Fat distribution (HIV) ( 21897333)
Interacting Genes		9 interacting genes: CTNNB1 DAXX EZR FYN ICAM1 LGALS1 LMNA MSN SIGLEC1	17 interacting genes: CD2 CD4 CD7 CD8A CDC42 GEMIN4 HRAS HSPB2 ITGB1 LGALS3BP MUC16 NLGN3 PTEN PTPRC SPN USP4 VPREB1
Entrez ID		6693	3956
HPRD ID		06770	01040
Ensembl ID		ENSG00000197471	ENSG00000100097
Uniprot IDs		A0A024R629 P16150	A0A384MR27 P09382
PDB IDs			1GZW 1W6M 1W6N 1W6O 1W6P 1W6Q 2KM2 2ZKN 3OY8 3OYW 3T2T 3W58 3W59 4Q1P 4Q1R 4Q26 4Q27 4Q2F 4XBL 4Y1U 4Y1V 4Y1X 4Y1Y 4Y1Z 4Y20 4Y22 4Y24 5MWT 5MWX 6B94 6F83
Enriched GO Terms of Interacting Partners?
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