MSN and VCAM1

Number of citations of the paper that reports this interaction (PubMedID 12082081)
158

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)
HPRD (in vivo, in vitro)

		MSN	VCAM1
Description		moesin	vascular cell adhesion molecule 1
Image
GO Annotations	Cellular Component	Uropod Extracellular Space Nucleus Cytoplasm Cytosol Cytoskeleton Plasma Membrane Microvillus Focal Adhesion Cell Surface Basolateral Plasma Membrane Apical Plasma Membrane Filopodium Pseudopodium Microvillus Membrane Vesicle Apical Part Of Cell Perinuclear Region Of Cytoplasm Extracellular Exosome Invadopodium Cell Periphery Blood Microparticle	Podosome Extracellular Space Early Endosome Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Microvillus External Side Of Plasma Membrane Cell Surface Filopodium Apical Part Of Cell Extracellular Exosome Alpha9-beta1 Integrin-vascular Cell Adhesion Molecule-1 Complex
	Molecular Function	Double-stranded RNA Binding Actin Binding Signaling Receptor Binding Structural Constituent Of Cytoskeleton Protein Binding Enzyme Binding Protein Kinase Binding Cell Adhesion Molecule Binding	Integrin Binding Primary Amine Oxidase Activity Cell Adhesion Molecule Binding
	Biological Process	Immunological Synapse Formation Cytoskeleton Organization Leukocyte Cell-cell Adhesion Regulation Of Cell Shape Regulation Of Cell Size Positive Regulation Of Gene Expression Viral Process Gland Morphogenesis Membrane To Membrane Docking Interleukin-12-mediated Signaling Pathway T Cell Proliferation Establishment Of Epithelial Cell Apical/basal Polarity Leukocyte Migration Establishment Of Endothelial Barrier T Cell Aggregation Cellular Response To Testosterone Stimulus Positive Regulation Of Podosome Assembly T Cell Migration Regulation Of Organelle Assembly Positive Regulation Of Protein Localization To Early Endosome Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Lymphocyte Migration Positive Regulation Of Early Endosome To Late Endosome Transport	Cell Adhesion Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Leukocyte Cell-cell Adhesion Cell-matrix Adhesion Amine Metabolic Process Cytokine-mediated Signaling Pathway Membrane To Membrane Docking B Cell Differentiation Extracellular Matrix Organization Heterotypic Cell-cell Adhesion Calcium-mediated Signaling Using Intracellular Calcium Source Positive Regulation Of T Cell Proliferation Regulation Of Immune Response Leukocyte Tethering Or Rolling Oxidation-reduction Process Interferon-gamma-mediated Signaling Pathway Cell-cell Adhesion In Response To Extracellular Stimulus Cellular Response To Amyloid-beta
Pathways		Recycling pathway of L1 Recycling pathway of L1 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Integrin cell surface interactions Interleukin-4 and Interleukin-13 signaling Interferon gamma signaling
Drugs			Ethanol Carvedilol Succinobucol
Diseases
GWAS		Male-pattern baldness ( 28196072)	Multiple sclerosis ( 31604244 24076602 21833088) SjÃ¶gren's syndrome ( 24097067)
Interacting Genes		28 interacting genes: BCAP31 CD44 CD46 CD93 CDK11B EZR ICAM1 ICAM2 ICAM3 L1CAM NCF1 NCF4 PLEC PPM1A PPM1B PRKAR2A PRKCQ ROCK1 SELL SELPLG SLC9A3R1 SMURF1 SPN TERF1 TRIM15 TSC1 VCAM1 VPS11	13 interacting genes: CCL17 CCL22 CTSG ELANE ETFA EXOSC2 EZR IL13 ITGAD ITGB1 ITGB7 MSN USP2
Entrez ID		4478	7412
HPRD ID		02399	01888
Ensembl ID		ENSG00000147065	ENSG00000162692
Uniprot IDs		P26038 V9HWC0	P19320
PDB IDs		1E5W 1EF1 1SGH	1IJ9 1VCA 1VSC
Enriched GO Terms of Interacting Partners?
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