LGALS1 and MUC16

Number of citations of the paper that reports this interaction (PubMedID 12615972)
36

Data Source:
HPRD (in vitro, in vivo)

		LGALS1	MUC16
Description		galectin 1	mucin 16, cell surface associated
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Intracellular Cell Nucleus Cytoplasm Endoplasmic Reticulum Lumen Cytosol Cell Surface Collagen-containing Extracellular Matrix Extracellular Exosome	Golgi Lumen Plasma Membrane Integral Component Of Membrane Extrinsic Component Of Membrane Vesicle Extracellular Exosome
	Molecular Function	RNA Binding Protein Binding Carbohydrate Binding Lactose Binding Identical Protein Binding Laminin Binding	Protein Binding
	Biological Process	Plasma Cell Differentiation Apoptotic Process Negative Regulation Of Cell-substrate Adhesion Negative Regulation Of Neuron Projection Development T Cell Costimulation Positive Regulation Of Erythrocyte Aggregation Response To Isolation Stress Response To Drug Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Post-translational Protein Modification Cellular Protein Metabolic Process Myoblast Differentiation Positive Regulation Of Viral Entry Into Host Cell Response To Axon Injury Cellular Response To Glucose Stimulus Cellular Response To Organic Cyclic Compound Positive Regulation Of Dendritic Cell Differentiation	Stimulatory C-type Lectin Receptor Signaling Pathway Cell Adhesion O-glycan Processing
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation	Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) Dectin-2 family O-linked glycosylation of mucins Termination of O-glycan biosynthesis
Drugs		Beta-Mercaptoethanol Thiodigalactoside 1,4-Dithiothreitol Artenimol	Oregovomab
Diseases
GWAS		Fat distribution (HIV) ( 21897333)	Asthma ( 30929738) Hepcidin/transferrin saturation ratio ( 27846281) Serum cancer antigen 125 levels ( 31666285) Tourette syndrome ( 30818990)
Interacting Genes		17 interacting genes: CD2 CD4 CD7 CD8A CDC42 GEMIN4 HRAS HSPB2 ITGB1 LGALS3BP MUC16 NLGN3 PTEN PTPRC SPN USP4 VPREB1	4 interacting genes: LGALS1 MSLN SUN2 UBC
Entrez ID		3956	94025
HPRD ID		01040	07548
Ensembl ID		ENSG00000100097	ENSG00000181143
Uniprot IDs		A0A384MR27 P09382	B3KY81 Q8WXI7
PDB IDs		1GZW 1W6M 1W6N 1W6O 1W6P 1W6Q 2KM2 2ZKN 3OY8 3OYW 3T2T 3W58 3W59 4Q1P 4Q1R 4Q26 4Q27 4Q2F 4XBL 4Y1U 4Y1V 4Y1X 4Y1Y 4Y1Z 4Y20 4Y22 4Y24 5MWT 5MWX 6B94 6F83
Enriched GO Terms of Interacting Partners?
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