SP4 and SP1

  • Number of citations of the paper that reports this interaction (PubMedID 7559627)
  • 39
  • Data Source:
  • HPRD (in vitro)

SP4

SP1

Description Sp4 transcription factor Sp1 transcription factor
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acute lymphoblastic leukemia (childhood) ( 29348612)
  • Amyotrophic lateral sclerosis (sporadic) ( 24529757)
  • Aspartate aminotransferase levels in non-alcoholic fatty liver disease ( 31311600)
  • Bipolar disorder ( 31043756)
  • General cognitive ability ( 29844566)
  • Major depressive disorder ( 20125088)
  • Major depressive disorder (broad) ( 20038947)
  • Multiple cancers (lung cancer, gastric cancer, and squamous cell carcinoma) ( 23103227)
  • Multisite chronic pain ( 31194737)
  • Schizophrenia ( 30285260)
  • Temporomandibular joint disorder ( 28081371)
  • Hypospadias (moderate to severe) ( 31856834)
  • Mean corpuscular hemoglobin ( 29403010)
  • Mean corpuscular volume ( 29403010)
  • Neutrophil percentage of white cells ( 27863252)
  • Parkinsonism in frontotemporal lobe dementia ( 29724592)
  • Percentage gas trapping ( 26030696)
  • Progressive supranuclear palsy ( 30089514)
  • Red blood cell count ( 27863252)
  • Reticulocyte count ( 27863252)
Interacting Genes 16 interacting genes: - ADAM15 ATXN7L1 BANP CIB3 COL8A1 E2F1 FOXP2 LMO3 NKX3-1 NRF1 POU2F1 PRR20A SERF2 SP1 ZBTB7A 145 interacting genes: AATF AHR AKT1 AR ARHGAP21 ARNT ATF7IP ATF7IP2 BCL11B BCL6 BCOR BRCA1 CASP3 CASP6 CASP7 CBX5 CCNA1 CCNA2 CCND1 CD2 CDK1 CDK2 CEBPB CSNK2A1 CTCFL CTNNB1 DDX5 DROSHA E2F1 E2F2 E2F3 EGR1 ELF1 EP300 ESR1 ESR2 ESRRA ESRRB ESRRG ETS1 GABPA GATA1 GATA3 GATA4 HBZ HCFC1 HDAC1 HDAC2 HIF1A HINT1 HLTF HMGA1 HNF4A HOXC11 HSPA8 HTT IL1B JUN KIF1A KLF10 KLF4 KLF6 LDB1 LMO2 MAPK1 MAPK3 MAPK8 MBD1 MEF2C MEF2D MIER1 MIS18BP1 MSX1 MTREX MYC MYCN MYOD1 MYOG NAP1L1 NCOR1 NCOR2 NEPRO NFKB1 NFKB2 NFYA NFYB NFYC NKX3-1 NOS3 NPM1 NR2F1 NR5A1 NUP62 OGT PARP1 PER3 PML POGZ POU2F1 PPIG PPP1R13L PRKCZ PRKDC PSIP1 PSMC5 PURA RARA RB1 RBBP4 RBL1 REL RELA RNF4 RORA RXRA SENP6 SF3A1 SHC1 SMAD2 SMAD3 SMAD4 SMARCC1 SMARCC2 SOX10 SOX8 SP3 SP4 SREBF1 SREBF2 SRF SUB1 TAF4 TAL1 TBP TLX3 TP53 TP73 TPI1 USP39 VEGFA VHL YY1 ZBTB16 ZBTB2 ZBTB7A
Entrez ID 6671 6667
HPRD ID 02764 01796
Ensembl ID ENSG00000105866 ENSG00000185591
Uniprot IDs A0A3B3IRW4 Q02446 Q32M51 P08047
PDB IDs 1SP1 1SP2 1VA1 1VA2 1VA3
Enriched GO Terms of Interacting Partners?
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